EVALUATION OF SERUM HEPATITIS B ANTIBODY LEVEL IN VACCINATED CHILDREN AFTER 14 YEARS IN KASHAN, IRAN

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TAGHAVI ARDAKANI A.; SOLTANI B.; SHARIF M.R.; MUSAVI GH.A.; KHADEMIAN M.

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Journal: Journal of Gorgan University of Medical Sciences Year:2012 | Volume:14 | Issue:3 (43) Page(s): 104-108

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Title

EVALUATION OF SERUM HEPATITIS B ANTIBODY LEVEL IN VACCINATED CHILDREN AFTER 14 YEARS IN KASHAN, IRAN

Author(s)

Keywords

HEPATITIS BQ2

HEPATITIS B VACCINEQ3

ANTI-HBSQ3

Abstract

Background and Objective: HEPATITIS B vaccination has been conducted in neonates in the routine vaccination in Iran since 1993. This study was carried out to evaluate the serum HEPATITIS B antibody level in vaccinated children after 14 years in Kashan, Iran.Materials and Methods: This prospetive cohort study was conducted on 200 fourteen-year-old children which were selected via a simple random sampling method in Kashan, Iran drung 2008-09. This subjects were have been vaccined according to the govermental guildline at 0, 2 and 6 months old. Two ml blood specimens were obtained from children and serum HEPATITIS B surface antibody (anti-HBs) and HEPATITIS B core antibody (anti-HBc) were determined by ELISA method. Immunity was interpreted as ANTI-HBS³10 IU/L. Data were analyzed using SPSS-13, Chi-Square and Fisher’s exat tests.Results: 92% girls and 95% boys, totally 187 (93.5%) children had serum ANTI-HBS³10 IU/L. Anti-HBc was positive in 3 (3%) girls and 5 (5%) boys, totally 8 (4%) which all of them had serum ANTI-HBS£10 IU/L. No case of positive HBs Ag was detected. Immunity was detected in 11 of 18 (61.1%) children with birth weight<2.5 kg and in 176 of 182 (96.7%) children with birth weight≥2.5 kg (P<0.05).Conclusion: The immunity following the complete series (0, 2, 6 months old) of HEPATITIS B vaccination remained detectable after 14 years.

Cites

PREVALENCE OF NATIONAL RESPONSIVENESS TO HBV VACCINE AFTER 22 YEARS OF IRANIAN EXPANDED PROGRAM ON IMMUNIZATION (EPI): A SYSTEMATIC REVIEW AND META-ANALYSIS STUDY

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APA: Copy

TAGHAVI ARDAKANI, A., SOLTANI, B., SHARIF, M.R., MUSAVI, GH.A., & KHADEMIAN, M.. (2012). EVALUATION OF SERUM HEPATITIS B ANTIBODY LEVEL IN VACCINATED CHILDREN AFTER 14 YEARS IN KASHAN, IRAN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 14(3 (43)), 104-108. SID. https://sid.ir/paper/79172/en

Vancouver: Copy

TAGHAVI ARDAKANI A., SOLTANI B., SHARIF M.R., MUSAVI GH.A., KHADEMIAN M.. EVALUATION OF SERUM HEPATITIS B ANTIBODY LEVEL IN VACCINATED CHILDREN AFTER 14 YEARS IN KASHAN, IRAN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;14(3 (43)):104-108. Available from: https://sid.ir/paper/79172/en

IEEE: Copy

A. TAGHAVI ARDAKANI, B. SOLTANI, M.R. SHARIF, GH.A. MUSAVI, and M. KHADEMIAN, “EVALUATION OF SERUM HEPATITIS B ANTIBODY LEVEL IN VACCINATED CHILDREN AFTER 14 YEARS IN KASHAN, IRAN,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 3 (43), pp. 104–108, 2012, [Online]. Available: https://sid.ir/paper/79172/en

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