ETIOLOGIES OF SEVERE INDIRECT HYPERBILIRUBNEMIA IN TERM NEONATES, GORGAN – IRAN

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MIRFAZELI A.; NAJAFI L.; CHERAGHALI R.; NOUHI A.H.

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Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2010 | Volume:11 | Issue:4 (32) Page(s): 82-86

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Title

ETIOLOGIES OF SEVERE INDIRECT HYPERBILIRUBNEMIA IN TERM NEONATES, GORGAN – IRAN

Author(s)

MIRFAZELI A. | NAJAFI L. | CHERAGHALI R. | NOUHI A.H. | Issue Writer Certificate

Keywords

NEONATAL INDIRECT HYPERBILIRUBINEMIAQ3

FREQUENCYQ3

ICTERQ3

KERN ICTERUSQ2

Abstract

Background and Objective: Jaundice is a common problem among neonate undiagnosed case finally lead to kern-icterus, with significant increasing rate of subsequent morbidity. This study was done to determine the etiology of of severe indirect hyperbilirubnemia in term neonates. Materials and Methods: This cross sectional descriptive study was performed in Taleghany hospital of Gorgan on neonates admitted due to severe hyperbilirubinemia from Sep 2004-Sep 2005. Severe hyperbilirubinemia was considered as bilirubin³18 mg/dl in term neonates weighing more than 2500g. Bilirubin (total, direct), blood culture, retic count, coombs test, level of glucose 6 phosphate dehydrogenase enzyme, complete blood cell count, mother's and neonate's blood group, urine culture and C-reactive protein tests were measured. Results: 766 term neonates (>2500g) were hospitalized due to hyperbilirubinemia. Severe hyperbilirubinemia was detected in 12% of cases (54 boys, 38 girls). The etiology of 41 cases were unknown, 25 cases were diagnosed as sepsis, 15 neonates were glucose 6 phosphate dehydrogenase enzyme deficient, 7 cases had UTI, 3 neonates had ABO incompatibility and one neonate was due to breast feeding. Conclusion: This study indicated that the most common etiology of severe hyperbilirubinemia in this region is unknown. Sepsis, glucose 6 phosphate dehydrogenase enzyme deficiency, UTI, ABO incompatibility and breast feeding were among other reasons for severe indirect hyperbilirubinemia.

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APA: Copy

MIRFAZELI, A., NAJAFI, L., CHERAGHALI, R., & NOUHI, A.H.. (2010). ETIOLOGIES OF SEVERE INDIRECT HYPERBILIRUBNEMIA IN TERM NEONATES, GORGAN – IRAN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 11(4 (32)), 82-86. SID. https://sid.ir/paper/79253/en

Vancouver: Copy

MIRFAZELI A., NAJAFI L., CHERAGHALI R., NOUHI A.H.. ETIOLOGIES OF SEVERE INDIRECT HYPERBILIRUBNEMIA IN TERM NEONATES, GORGAN – IRAN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;11(4 (32)):82-86. Available from: https://sid.ir/paper/79253/en

IEEE: Copy

A. MIRFAZELI, L. NAJAFI, R. CHERAGHALI, and A.H. NOUHI, “ETIOLOGIES OF SEVERE INDIRECT HYPERBILIRUBNEMIA IN TERM NEONATES, GORGAN – IRAN,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 11, no. 4 (32), pp. 82–86, 2010, [Online]. Available: https://sid.ir/paper/79253/en

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