DECREASE OF ERYTHROCYTE CHOLINESTERASE IN PESTICIDE FACTORY WORKERS

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JOUSHAGHANI H.R.; AHMADI ALI REZA; BEHNAMPOUR N.

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Journal: Journal of Gorgan University of Medical Sciences Year:2006 | Volume:8 | Issue:4 (20) Page(s): 23-27

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Title

DECREASE OF ERYTHROCYTE CHOLINESTERASE IN PESTICIDE FACTORY WORKERS

Author(s)

JOUSHAGHANI H.R. | AHMADI ALI REZA | BEHNAMPOUR N. | Issue Writer Certificate

Keywords

CHOLINESTERASEQ3

ERYTHROCYTEQ3

ORGANOPHOSPHATEQ3

PESTICIDEQ3

Abstract

Background & Objective: Two enzymes have the ability to hydrolyze acetylcholine. One is acetyl CHOLINESTERASE, which is called true CHOLINESTERASE, it is found in ERYTHROCYTEs. The other CHOLINESTERASE is pseudo CHOLINESTERASE, it is found in serum. Some chemical components of ORGANOPHOSPHATEs group and carbamates affected CHOLINESTERASE activity. Determination of CHOLINESTERASE has application in diagnosis of liver disease, liver damage by insecticide and assessment of fatty liver. PESTICIDE factory workers are one group of peoples which are exposed of poisoning by PESTICIDE.Materials & Methods: This research in 2005 performed in PESTICIDE producers. In two stages (3 month interval) from 58 of personal blood was drown.Results: Mean of ERYTHROCYTE CHOLINESTERASE in first stage was 48.5±11.2 IU/gHb and second stage was 37.9±17.3 IU/gHb. Decrease of ERYTHROCYTE CHOLINESTERASE was significant differences (paired t test, P<0.05). Increase of serum AST was not statistically significant. Increase of serum ALT and Albumin was significant differences (paired t test, p<0.05). In 15 individual (25.9 %) CHOLINESTERASE decrease more than 35% and in 16 workers (27.6 %) ERYTHROCYTE CHOLINESTERASE decrease between 26-35%.Conclusion: Since in more than 26% of personnel CHOLINESTERASE decreased over than 35%, routine assessment of CHOLINESTERASE in similar factory, is recommended.

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مقایسه فعالیت آنزیم کولین استراز گلبول قرمز و پلاسما در افراد سالم و کارگران در تماس با سموم ارگانوفسفره

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APA: Copy

JOUSHAGHANI, H.R., AHMADI, ALI REZA, & BEHNAMPOUR, N.. (2006). DECREASE OF ERYTHROCYTE CHOLINESTERASE IN PESTICIDE FACTORY WORKERS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 8(4 (20)), 23-27. SID. https://sid.ir/paper/79587/en

Vancouver: Copy

JOUSHAGHANI H.R., AHMADI ALI REZA, BEHNAMPOUR N.. DECREASE OF ERYTHROCYTE CHOLINESTERASE IN PESTICIDE FACTORY WORKERS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;8(4 (20)):23-27. Available from: https://sid.ir/paper/79587/en

IEEE: Copy

H.R. JOUSHAGHANI, ALI REZA AHMADI, and N. BEHNAMPOUR, “DECREASE OF ERYTHROCYTE CHOLINESTERASE IN PESTICIDE FACTORY WORKERS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 4 (20), pp. 23–27, 2006, [Online]. Available: https://sid.ir/paper/79587/en

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