RUBELLA VACCINATION IN PREGNANCY AND SEROLOGIC SITUATION OF INFANTS

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KHOURI E.; BANI AGHIL A.S.; AZARHOUSH R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2009 | Volume:10 | Issue:4 (28) Page(s): 44-48

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Information Journal Paper

Title

RUBELLA VACCINATION IN PREGNANCY AND SEROLOGIC SITUATION OF INFANTS

Author(s)

KHOURI E. | BANI AGHIL A.S. | AZARHOUSH R. | Issue Writer Certificate

Keywords

RUBELLA VACCINEQ3

PREGNANCYQ3

CONGENITAL RUBELLA SYNDROME (CRS)Q3

MR VACCINEQ2

RUBELLA IGMQ3

Abstract

Background & Objective: RUBELLA VACCINE is prepared with live virus thus if it injects during abstinence period, it can cause fetal risks. The aim of study was to evaluate RUBELLA IGM among infants of women who were vaccinated against rubella during 3 months pre-or post-conception (abstinence period).Materials & Methods: This cohort study was done on 253 mothers, including 116 mothers as cases and 137 mothers as controls. The case group inadvertently had received MR VACCINE (RA27/3) during abstinence period. The control group selected randomly from similar delivery center that admitted for delivery. The background and confounding factors was matched between the control and case groups. In both groups after delivery, cord RUBELLA IGM was measured by ELISA for serological diagnosis of infant infection. Data was analyzed by Chi-square and T-student tests.Results: The findings showed that the number of positive IGM infant was similar in both groups (One positive IGM in each group). In spite of no significant difference between the case and the control groups, the maximum theoretical risk in this study was 4.392% (RR=1.091; 95% CI=0.271-4.392).Conclusion: Although no significant difference was found from the point of infants with an IgM+ serology in two groups, according to the risk ratio obtained in this study, we still recommend vaccination should be avoided during abstinence period.

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APA: Copy

KHOURI, E., BANI AGHIL, A.S., & AZARHOUSH, R.. (2009). RUBELLA VACCINATION IN PREGNANCY AND SEROLOGIC SITUATION OF INFANTS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 10(4 (28)), 44-48. SID. https://sid.ir/paper/79631/en

Vancouver: Copy

KHOURI E., BANI AGHIL A.S., AZARHOUSH R.. RUBELLA VACCINATION IN PREGNANCY AND SEROLOGIC SITUATION OF INFANTS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;10(4 (28)):44-48. Available from: https://sid.ir/paper/79631/en

IEEE: Copy

E. KHOURI, A.S. BANI AGHIL, and R. AZARHOUSH, “RUBELLA VACCINATION IN PREGNANCY AND SEROLOGIC SITUATION OF INFANTS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 10, no. 4 (28), pp. 44–48, 2009, [Online]. Available: https://sid.ir/paper/79631/en

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