THE ANALGESIC EFFECTS OF ZIZIPHORA TENUIOR IN ADULT MALE MICE

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GHORBANI RANJBARY ALI; YARYAR MOHAMADREZA; JOYBAR FATEMEH; GHORBANI RANJBARY NAZANIN

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Journal: Yafteh Year:2015 | Volume:16 | Issue:4 (62) Page(s): 62-69

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Title

THE ANALGESIC EFFECTS OF ZIZIPHORA TENUIOR IN ADULT MALE MICE

Author(s)

GHORBANI RANJBARY ALI | YARYAR MOHAMADREZA | JOYBAR FATEMEH | GHORBANI RANJBARY NAZANIN | Issue Writer Certificate

Keywords

ZIZIPHORA TENUIORQ2

PAINQ2

FORMALIN TESTQ3

MICEQ2

Abstract

Background: ZIZIPHORA TENUIOR is one of the traditional medicinal plants. The main active chemical compounds in this plant is Pulegone that its anti-inflammatory and its analgesic effects is well specified. In the present study, the analgesic effects of ZIZIPHORA TENUIOR native of Sirjan zone (underflow) on the adult male MICE was studied.Materials and Methods: In this study, after collecting leaf and twigs in Sirjan zone, The extract of ZIZIPHORA TENUIOR was prepared by soaking method. Action of analgesia was evaluated using the FORMALIN TEST. Hydro alcoholic extract at concentrations of 50, 100 and 150 mg per kg of body weight, was injected intraperitoneally. The control group had no treatment, and case group received drug solvent, normal saline intraperitoneally, and group 6 received morphine to rate of 0.2 mg kg. The data gathered and analyzed by SPSS 17 software and ANOVA statistical test in a significant level (P<0.05).Results: The results of this study showed that in adult male rats intraperitoneal injection of ZIZIPHORA TENUIOR of Pariz zone (Sirjan) at concentrations of 50, 100 and 150 mg kg as morphine reduced the primary and secondary phases of PAIN which induced by formalin.Conclusion: The data showed that the medicinal herb of ZIZIPHORA TENUIOR, has analgesic effects on MICE and this plant should be considered in future treatments and it can be a good alternative to chemical drugs.

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APA: Copy

GHORBANI RANJBARY, ALI, YARYAR, MOHAMADREZA, JOYBAR, FATEMEH, & GHORBANI RANJBARY, NAZANIN. (2015). THE ANALGESIC EFFECTS OF ZIZIPHORA TENUIOR IN ADULT MALE MICE. YAFTEH, 16(4 (62)), 62-69. SID. https://sid.ir/paper/79790/en

Vancouver: Copy

GHORBANI RANJBARY ALI, YARYAR MOHAMADREZA, JOYBAR FATEMEH, GHORBANI RANJBARY NAZANIN. THE ANALGESIC EFFECTS OF ZIZIPHORA TENUIOR IN ADULT MALE MICE. YAFTEH[Internet]. 2015;16(4 (62)):62-69. Available from: https://sid.ir/paper/79790/en

IEEE: Copy

ALI GHORBANI RANJBARY, MOHAMADREZA YARYAR, FATEMEH JOYBAR, and NAZANIN GHORBANI RANJBARY, “THE ANALGESIC EFFECTS OF ZIZIPHORA TENUIOR IN ADULT MALE MICE,” YAFTEH, vol. 16, no. 4 (62), pp. 62–69, 2015, [Online]. Available: https://sid.ir/paper/79790/en

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