THE EFFECT OF EIGHT WEEKS OF AEROBIC TRAINING ON LEPTIN, INTERLUKIN-6, AND TUMOR NECROSIS FACTOR-ALPHA LEVELS IN INACTIVE ELDERLY WOMEN

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DOOSTDAR MEHDI; Fathei Mehrdad; HEJAZI KEYVAN; Kiani Gol Mojtaba

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Journal: Pathobiology Research Year:2017 | Volume:19 | Issue:4 Page(s): 13-25

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Title

THE EFFECT OF EIGHT WEEKS OF AEROBIC TRAINING ON LEPTIN, INTERLUKIN-6, AND TUMOR NECROSIS FACTOR-ALPHA LEVELS IN INACTIVE ELDERLY WOMEN

Author(s)

DOOSTDAR MEHDI | Fathei Mehrdad | HEJAZI KEYVAN | Kiani Gol Mojtaba | Issue Writer Certificate

Keywords

LEPTINQ3

INTERLUKIN-6Q2

AEROBIC EXERCISESQ2

ELDERLY WOMENQ1

Abstract

Objective: Atherosclerosis is the most common cause of coronary heart disease and a major cause of ischemic heart diseases. We have investigated the effect of eight weeks of aerobic training on the serum levels of LEPTIN, IL-6, and TNF-α in inactive ELDERLY WOMEN.Methods: In this semi-experimental study, participants were selected by convenience sampling. We divided 21 subjects into two groups - active (n=10) and non-active (n=11). The program training included 60 min per session, 3 times per week for 8 weeks of aerobic exercise with 50-70 HRR%. Blood samples were taken before and after 8 weeks of aerobic training. We used the t-test for dependent and independent samples for intra- and intergroup comparisons. For all statistical comparisons, the level of significance was set at P<0.05.Results: The aerobic training groups had a significant reduction in LEPTIN (P=0.001), IL-6 (P=0.01), and TNF-α (P=0.001) after 8 weeks of aerobic training compared with the control group. The intergroup variations in weight, BMI, LEPTIN, and TNF-a had a significant change (P<0.05).Conclusion: The results of the present study suggested that endurance training decreased LEPTIN, IL-6, and TNF-a levels, effectively improved cardiovascular health, and reduced the risk of atherosclerosis.

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APA: Copy

DOOSTDAR, MEHDI, Fathei, Mehrdad, HEJAZI, KEYVAN, & Kiani Gol, Mojtaba. (2017). THE EFFECT OF EIGHT WEEKS OF AEROBIC TRAINING ON LEPTIN, INTERLUKIN-6, AND TUMOR NECROSIS FACTOR-ALPHA LEVELS IN INACTIVE ELDERLY WOMEN. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), 19(4 ), 13-25. SID. https://sid.ir/paper/81091/en

Vancouver: Copy

DOOSTDAR MEHDI, Fathei Mehrdad, HEJAZI KEYVAN, Kiani Gol Mojtaba. THE EFFECT OF EIGHT WEEKS OF AEROBIC TRAINING ON LEPTIN, INTERLUKIN-6, AND TUMOR NECROSIS FACTOR-ALPHA LEVELS IN INACTIVE ELDERLY WOMEN. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES)[Internet]. 2017;19(4 ):13-25. Available from: https://sid.ir/paper/81091/en

IEEE: Copy

MEHDI DOOSTDAR, Mehrdad Fathei, KEYVAN HEJAZI, and Mojtaba Kiani Gol, “THE EFFECT OF EIGHT WEEKS OF AEROBIC TRAINING ON LEPTIN, INTERLUKIN-6, AND TUMOR NECROSIS FACTOR-ALPHA LEVELS IN INACTIVE ELDERLY WOMEN,” PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), vol. 19, no. 4 , pp. 13–25, 2017, [Online]. Available: https://sid.ir/paper/81091/en

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