EFFECT OF PROTEIN AND DNA COMPONENTS OF TOXOPLASMA GONDII ON IL-12 PRODUCTION FROM DENDRITIC CELLS AND T CELL PROLIFERATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AMARI A.; RAZAVI S.A.R.; JAMALI A.; AMINI SARDROUD A.A.; MOTAMEDI MASOUMEH; SHOJAEI SAEIDEH; ANSARIPOUR B.; HAJATI J.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Pathobiology Research Year:2009 | Volume:12 | Issue:3 Page(s): 1-8

Download Full-Text

Persian Verion

View:

848

Download:

Cites:

Information Journal Paper

Title

EFFECT OF PROTEIN AND DNA COMPONENTS OF TOXOPLASMA GONDII ON IL-12 PRODUCTION FROM DENDRITIC CELLS AND T CELL PROLIFERATION

Author(s)

Keywords

DENDRITIC CELLSQ3

TOXOPLASMA GONDIIQ3

IL-12Q3

Abstract

Objective: The aim of the present study was to investigate the effect of protein and DNA components of TOXOPLASMA GONDII on maturation of DENDRITIC CELLS and their efficiency in IL-12 production and proliferation of T cells.Materials and Methods: for DC generation, Bone marrow cells were cultured in the presence of GMCSF and IL-4 for 5 days. Tumor lysate and protein or DNA components of TOXOPLASMA GONDII were added to the culture media and incubated for another 2 days. LPS was added as control for DC maturation. Proliferation of T cells was determined by MLR and IL-12 production was measured by ELISA kit. Maturation of dendritic cell was determined by flowcytometry.Results: DCs treatment with protein components of TOXOPLASMA GONDII caused a significant increase in IL-12 production and proliferation of T cells (P<0.001).Conclusions: Different compositions of microbial body like protein and DNA components of TOXOPLASMA GONDII can cause augmentation of antigen presentation capacity of DC and their IL-12 production capability. Among these components the protein was more effective as compared to DNA.

Cites

No record.

References

No record.

Cite

APA: Copy

AMARI, A., RAZAVI, S.A.R., JAMALI, A., AMINI SARDROUD, A.A., MOTAMEDI, MASOUMEH, SHOJAEI, SAEIDEH, ANSARIPOUR, B., & HAJATI, J.. (2009). EFFECT OF PROTEIN AND DNA COMPONENTS OF TOXOPLASMA GONDII ON IL-12 PRODUCTION FROM DENDRITIC CELLS AND T CELL PROLIFERATION. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), 12(3), 1-8. SID. https://sid.ir/paper/81127/en

Vancouver: Copy

AMARI A., RAZAVI S.A.R., JAMALI A., AMINI SARDROUD A.A., MOTAMEDI MASOUMEH, SHOJAEI SAEIDEH, ANSARIPOUR B., HAJATI J.. EFFECT OF PROTEIN AND DNA COMPONENTS OF TOXOPLASMA GONDII ON IL-12 PRODUCTION FROM DENDRITIC CELLS AND T CELL PROLIFERATION. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES)[Internet]. 2009;12(3):1-8. Available from: https://sid.ir/paper/81127/en

IEEE: Copy

A. AMARI, S.A.R. RAZAVI, A. JAMALI, A.A. AMINI SARDROUD, MASOUMEH MOTAMEDI, SAEIDEH SHOJAEI, B. ANSARIPOUR, and J. HAJATI, “EFFECT OF PROTEIN AND DNA COMPONENTS OF TOXOPLASMA GONDII ON IL-12 PRODUCTION FROM DENDRITIC CELLS AND T CELL PROLIFERATION,” PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), vol. 12, no. 3, pp. 1–8, 2009, [Online]. Available: https://sid.ir/paper/81127/en

Related Journal Papers