EFFECT OF LOW–LEVEL HELIUM-NEON LASER IRRADIATION ON THE RELEASE OF INTERLEUKIN 6 AND BASIC FIBROBLAST GROWTH FACTOR FROM CULTURED HUMAN FIBROBLASTS IN HIGH GLUCOSE MEDIUM

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ESMAEELINEJAD M.; BAYAT M.; DADPAY M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Anatomical Sciences Journal Year:2012 | Volume:9 | Issue:37 Page(s): 296-304

Download Full-Text

Persian Verion

View:

657

Download:

Cites:

Information Journal Paper

Title

EFFECT OF LOW–LEVEL HELIUM-NEON LASER IRRADIATION ON THE RELEASE OF INTERLEUKIN 6 AND BASIC FIBROBLAST GROWTH FACTOR FROM CULTURED HUMAN FIBROBLASTS IN HIGH GLUCOSE MEDIUM

Author(s)

ESMAEELINEJAD M. | BAYAT M. | DADPAY M. | Issue Writer Certificate

Keywords

BASIC FIBROBLAST GROWTH FACTORQ3

HUMAN SKIN FIBROBLASTSQ2

INTERLEUKIN 6Q2

LOW LEVEL LASER THERAPYQ2

Abstract

Purpose: LOW LEVEL LASER THERAPY is suggested as a new therapeutic method in diabetic wound healing. This survey aimed to evaluate the effects of low level laser on human fibroblasts cultured in high glucose cultures. Materials and Methods: The HUMAN SKIN FIBROBLASTS were cultured under standard condition. The cells were cultured in high glucose culture medium (15mM/L) for a week and two weeks before laser irradiation. The irradiation was carried out with Helium-Neon (He-Ne) laser unit on the case groups. Control cells did not receive laser. The cells were irradiated with three doses of 0.5, 1 and 2 J/cm2 on three consecutive days. The releasing rates of INTERLEUKIN 6 and Fibroblast growth factor were evaluated by ELISA (enzyme-linked immunoabsorbent assay). Data were analyzed by student t test or Mann-Whitney-U test.Results: All three doses of 0.5 (p=0.049), 1 J/cm2 (p=0.027) had a stimulatory effect on releasing rate of IL-6 of the fibroblasts cultured in culture medium with high glucose concentration in comparison with hyper glycemic non irradiated cells. LOW LEVEL LASER THERAPY (LLLT) with energy density of 2 J/cm2 induced the release of bFGF of the fibroblasts cultured in culture medium with high glucose concentration for one and two weeks (p=0.047 and p=0.04 respectively).Conclusion: This study showed that LLLT has stimulatory effects on the release of INTERLEUKIN 6 and BASIC FIBROBLAST GROWTH FACTOR from cultured human fibroblasts in high glucose medium in one week and two-week tests.

Cites

No record.

References

No record.

Cite

APA: Copy

ESMAEELINEJAD, M., BAYAT, M., & DADPAY, M.. (2012). EFFECT OF LOW–LEVEL HELIUM-NEON LASER IRRADIATION ON THE RELEASE OF INTERLEUKIN 6 AND BASIC FIBROBLAST GROWTH FACTOR FROM CULTURED HUMAN FIBROBLASTS IN HIGH GLUCOSE MEDIUM. JOURNAL OF IRANIAN ANATOMICAL SCIENCES, 9(37), 296-304. SID. https://sid.ir/paper/81523/en

Vancouver: Copy

ESMAEELINEJAD M., BAYAT M., DADPAY M.. EFFECT OF LOW–LEVEL HELIUM-NEON LASER IRRADIATION ON THE RELEASE OF INTERLEUKIN 6 AND BASIC FIBROBLAST GROWTH FACTOR FROM CULTURED HUMAN FIBROBLASTS IN HIGH GLUCOSE MEDIUM. JOURNAL OF IRANIAN ANATOMICAL SCIENCES[Internet]. 2012;9(37):296-304. Available from: https://sid.ir/paper/81523/en

IEEE: Copy

M. ESMAEELINEJAD, M. BAYAT, and M. DADPAY, “EFFECT OF LOW–LEVEL HELIUM-NEON LASER IRRADIATION ON THE RELEASE OF INTERLEUKIN 6 AND BASIC FIBROBLAST GROWTH FACTOR FROM CULTURED HUMAN FIBROBLASTS IN HIGH GLUCOSE MEDIUM,” JOURNAL OF IRANIAN ANATOMICAL SCIENCES, vol. 9, no. 37, pp. 296–304, 2012, [Online]. Available: https://sid.ir/paper/81523/en

Related Journal Papers