THE EFFECTS OF CYTOTOXICITY OF ASTRAGALUS CYSTOSUS ON THE HELA CELLS BY USING MTT METHOD

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SADAT ALDAGHI LEILA; DEHPOUR JOOYBARI ABBAS ALI; NEMATI FARKHONDEH; MIR DASHTI REZA; EKRAMI RAHIM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2014 | Volume:20 | Issue:5 (SPECIAL) Page(s): 603-610

Download Full-Text

Persian Verion

View:

2,290

Download:

Cites:

Information Journal Paper

Title

THE EFFECTS OF CYTOTOXICITY OF ASTRAGALUS CYSTOSUS ON THE HELA CELLS BY USING MTT METHOD

Author(s)

Keywords

ASTRAGALUS CYSTOSUSQ2

HELAQ2

CYTOTOXICITYQ2

ETHANOL EXTRACTQ2

Abstract

Background & objectives: Cancer prevention and treatment by medicinal plants for a long was is one of the most challenging areas of research. Among them, some plants species could suppress or kill tumor cells via apoptosis or necrosis. One of these plants is Astragalus. The purpose of this study was investigating the anti-cancer effects of this plant.Material & method: The cancer cell lines obtained from Pasteur Institute of Iran. The cells were cultured in RPMI 1640. Then the cells have effected from the presence of various concentrations (0.156, 0.312, 0.625, 1.25, 2.5, 5, 7.5 and 10 mg/ml) of ASTRAGALUS CYSTOSUS. After 72 hours the rate of CYTOTOXICITY was determined by using MTT test. These statistical analyses carried out with a significant level of 0.05 and t-test with excel software.Findings: These findings indicate that the extract of ASTRAGALUS CYSTOSUS on HELA cancer cell lines had CYTOTOXICITY in all concentrations and the highest inhibition was 7.5 and 10 mg/ml concentrations. The rate of inhibition in higher concentrations such as 10mg/m1 was equal to 28.98% which is the highest one.Conclusion: Regarding that the extract of ASTRAGALUS CYSTOSUS had CYTOTOXICITY on HELA cancer cells, further studies can be performed on animal model and clinical trial so that Astragalus used as an anticancer drug.

Cites

No record.

References

No record.

Cite

APA: Copy

SADAT ALDAGHI, LEILA, DEHPOUR JOOYBARI, ABBAS ALI, NEMATI, FARKHONDEH, MIR DASHTI, REZA, & EKRAMI, RAHIM. (2014). THE EFFECTS OF CYTOTOXICITY OF ASTRAGALUS CYSTOSUS ON THE HELA CELLS BY USING MTT METHOD. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 20(5 (SPECIAL)), 603-610. SID. https://sid.ir/paper/82031/en

Vancouver: Copy

SADAT ALDAGHI LEILA, DEHPOUR JOOYBARI ABBAS ALI, NEMATI FARKHONDEH, MIR DASHTI REZA, EKRAMI RAHIM. THE EFFECTS OF CYTOTOXICITY OF ASTRAGALUS CYSTOSUS ON THE HELA CELLS BY USING MTT METHOD. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;20(5 (SPECIAL)):603-610. Available from: https://sid.ir/paper/82031/en

IEEE: Copy

LEILA SADAT ALDAGHI, ABBAS ALI DEHPOUR JOOYBARI, FARKHONDEH NEMATI, REZA MIR DASHTI, and RAHIM EKRAMI, “THE EFFECTS OF CYTOTOXICITY OF ASTRAGALUS CYSTOSUS ON THE HELA CELLS BY USING MTT METHOD,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 20, no. 5 (SPECIAL), pp. 603–610, 2014, [Online]. Available: https://sid.ir/paper/82031/en

Related Journal Papers