The effect of concurrent aerobic training with Origanum vulgare Hydro Ethanolic Extract supplementation on gene expression of myocardial apoptosis proteins in male rats

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Rahimzadeh Ghader; Azarbaijani Mohamad Ali; Matin Homaei Hasan

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Journal: Journal of Sabzevar University of Medical Sciences Year:2019 | Volume:26 | Issue:2 Page(s): 161-170

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Title

The effect of concurrent aerobic training with Origanum vulgare Hydro Ethanolic Extract supplementation on gene expression of myocardial apoptosis proteins in male rats

Author(s)

Rahimzadeh Ghader | Azarbaijani Mohamad Ali | Matin Homaei Hasan | Issue Writer Certificate

Keywords

Aerobic ExerciseQ2

Origanum vulgareQ1

ApoptosisQ1

RatQ2

Abstract

Background: Today, the use of supplements and herbal extracts has been widely used to prevent exercise induced Apoptosis and improve exercise training adaptations. Thus, the present study examined the effect of the 12 weeks aerobic training with Origanum vulgare ethanolic Extract supplementation on the myocardial Apoptosis in young male Rats. Methods: In this experimental study, 40 male Wistar Rats (8 weeks old)with an average(weight 129± 17. 86 in gr)randomly divided in five equal groups: basic(n=8), control(n=8), Origanum vulgare(n=8), aerobic training(n=8)and aerobic training-Origanum vulgare(n=8). The aerobic training and aerobic training-Origanum vulgare groups participated in a 12-week program (5 sessions of 10-60 minutes each week, with an intensity of 75-80% of maximum oxygen consumption) running on animal treadmill (15% incline and 24-33 m/s). Also, Origanum vulgare Ethanolic extract was used for supplementation. Forty-eight hours after the last exercise session, a part of the left venticular tissue of the heart was removed and expression of Bax, Bcl2 and caspase-9 proteins was investigated using RT-PCR method. Data were analyzed byTwo-way ANOVA test (P

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APA: Copy

Rahimzadeh, Ghader, Azarbaijani, Mohamad Ali, & Matin Homaei, Hasan. (2019). The effect of concurrent aerobic training with Origanum vulgare Hydro Ethanolic Extract supplementation on gene expression of myocardial apoptosis proteins in male rats. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 26(2 ), 161-170. SID. https://sid.ir/paper/82169/en

Vancouver: Copy

Rahimzadeh Ghader, Azarbaijani Mohamad Ali, Matin Homaei Hasan. The effect of concurrent aerobic training with Origanum vulgare Hydro Ethanolic Extract supplementation on gene expression of myocardial apoptosis proteins in male rats. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;26(2 ):161-170. Available from: https://sid.ir/paper/82169/en

IEEE: Copy

Ghader Rahimzadeh, Mohamad Ali Azarbaijani, and Hasan Matin Homaei, “The effect of concurrent aerobic training with Origanum vulgare Hydro Ethanolic Extract supplementation on gene expression of myocardial apoptosis proteins in male rats,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 2 , pp. 161–170, 2019, [Online]. Available: https://sid.ir/paper/82169/en

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