COMPARISON OF RAT POSTERIOR TIBIAL NERVE REPAIR WITH SUTURE AND SINGLE DONOR HUMAN FIBRIN ADHESIVE

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ERFANIAN REZA; FIROUZI MASOUMEH; NABIAN MOHAMMAD HOSSEIN; DARVISHZADEH MASOUD; ORIADI ZANJANI LEILA; ABDOLLAHZADEGAN SHAYAN; SHAHRYAR KAMRANI REZA

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Journal: IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY Year:2010 | Volume:8 | Issue:1 (30) Page(s): 1-8

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Title

COMPARISON OF RAT POSTERIOR TIBIAL NERVE REPAIR WITH SUTURE AND SINGLE DONOR HUMAN FIBRIN ADHESIVE

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Keywords

TIBIAL NERVEQ3

FIBRIN TISSUE ADHESIVEQ3

MATERIALS TESTINGQ3

Abstract

Background: The use of fibrin adhesive has broad background in medicine and peripheral nerve repair. The physical properties of these adhesives has restricted their usage. This experiment studied the performance and physical characteristics of fibrin glue (which is prepared from single donor human plasma) in the repair of posterior TIBIAL NERVE of rat.Methods: In this study, posterior TIBIAL NERVEs of 40 rats were transected. In group A no repair was performed; in group B repair was done by one micro suture; in group C repair was done by three microsutures; in group D by one suture plus fibrin adhesive; and in group E repair was done just with fibrin adhesive. After 8 weeks of follow-up, Tibial Function Index; and at the end of the study, adhesive strength inflammation and scar formation were measured.Results: Functional recovery in the eighth week for groups A and E were significantly lower than groups B and C (p=.03).No rat repaired with fibrin adhesive had dehiscence, while half of rats in group A had complete dehiscence - was significantly higher than the others groups (p=.002). Inflammation and scar tissue were similar between the groups.Conclusion: The produced fibrin adhesive provides required adhesive and could hold nerve stumps in long term.

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APA: Copy

ERFANIAN, REZA, FIROUZI, MASOUMEH, NABIAN, MOHAMMAD HOSSEIN, DARVISHZADEH, MASOUD, ORIADI ZANJANI, LEILA, ABDOLLAHZADEGAN, SHAYAN, & SHAHRYAR KAMRANI, REZA. (2010). COMPARISON OF RAT POSTERIOR TIBIAL NERVE REPAIR WITH SUTURE AND SINGLE DONOR HUMAN FIBRIN ADHESIVE. IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY, 8(1 (30)), 1-8. SID. https://sid.ir/paper/85240/en

Vancouver: Copy

ERFANIAN REZA, FIROUZI MASOUMEH, NABIAN MOHAMMAD HOSSEIN, DARVISHZADEH MASOUD, ORIADI ZANJANI LEILA, ABDOLLAHZADEGAN SHAYAN, SHAHRYAR KAMRANI REZA. COMPARISON OF RAT POSTERIOR TIBIAL NERVE REPAIR WITH SUTURE AND SINGLE DONOR HUMAN FIBRIN ADHESIVE. IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY[Internet]. 2010;8(1 (30)):1-8. Available from: https://sid.ir/paper/85240/en

IEEE: Copy

REZA ERFANIAN, MASOUMEH FIROUZI, MOHAMMAD HOSSEIN NABIAN, MASOUD DARVISHZADEH, LEILA ORIADI ZANJANI, SHAYAN ABDOLLAHZADEGAN, and REZA SHAHRYAR KAMRANI, “COMPARISON OF RAT POSTERIOR TIBIAL NERVE REPAIR WITH SUTURE AND SINGLE DONOR HUMAN FIBRIN ADHESIVE,” IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY, vol. 8, no. 1 (30), pp. 1–8, 2010, [Online]. Available: https://sid.ir/paper/85240/en

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