OSTEONECROSIS FOLLOWING TEMGESIC/ NORGESIC ADDICTION

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KAZEMI SEYED MORTEZA; HOSSEINZADEH HAMID REZA; AALAMI HARANDI A.; RANJPOUR F.

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Paper Information

Journal: IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY Year:2007 | Volume:5 | Issue:3 (19) Page(s): 152-155

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Title

OSTEONECROSIS FOLLOWING TEMGESIC/ NORGESIC ADDICTION

Author(s)

KAZEMI SEYED MORTEZA | HOSSEINZADEH HAMID REZA | AALAMI HARANDI A. | RANJPOUR F. | Issue Writer Certificate

Keywords

OSTEONECROSISQ3

FEMUR HEAD NECROSISQ3

DRUG ADDICTIONQ3

OPIOIDQ3

RELATED DISORDERSQ3

Abstract

Background: A vascular necrosis- a common reason for hip reconstruction- can follow use of some medications including glucocorticoids. Temgesic and norgesic are two analgesic antagonists with high concentration on steroids on steroids and can produce OSTEONECROSIS.Methods: In a case series study, cased of OSTEONECROSIS in Akhtar hospital in Tehran with history of temgesic and norgesic abuse were identified in a 2 year period. The hospital charts of 11 cases with such characteristics were evaluated.Results: Eleven cases with mean age of 37.42±5.55 years comprised the study group. Five cases had used norgesic, 5 temgesic and 1 patient had used both of those agents. The average drug dosage was 4.36±2.29 vials per day for an average of 4.9±2.9 months. Onset of symptoms was 11.36±2.79 months after drug usage on average. Three cases had skin stria and 7 patients had localized obesity, both suggesting steroid effect. Bilateral involvement of bone ends was observed in all, while 3 cases had more than two joints affected.Conclusions: Norgesic and temgesic cause OSTEONECROSIS with severe joint destruction. Raising the awareness of general public and physicians towards such a devastating complication is warranted.

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APA: Copy

KAZEMI, SEYED MORTEZA, HOSSEINZADEH, HAMID REZA, AALAMI HARANDI, A., & RANJPOUR, F.. (2007). OSTEONECROSIS FOLLOWING TEMGESIC/ NORGESIC ADDICTION. IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY, 5(3 (19)), 152-155. SID. https://sid.ir/paper/85549/en

Vancouver: Copy

KAZEMI SEYED MORTEZA, HOSSEINZADEH HAMID REZA, AALAMI HARANDI A., RANJPOUR F.. OSTEONECROSIS FOLLOWING TEMGESIC/ NORGESIC ADDICTION. IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY[Internet]. 2007;5(3 (19)):152-155. Available from: https://sid.ir/paper/85549/en

IEEE: Copy

SEYED MORTEZA KAZEMI, HAMID REZA HOSSEINZADEH, A. AALAMI HARANDI, and F. RANJPOUR, “OSTEONECROSIS FOLLOWING TEMGESIC/ NORGESIC ADDICTION,” IRANIAN JOURNAL OF ORTHOPAEDIC SURGERY, vol. 5, no. 3 (19), pp. 152–155, 2007, [Online]. Available: https://sid.ir/paper/85549/en

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