RESULTS OF TRANSARTERIAL CHEMOEMBOLIZATION (TACE) IN A GROUP OF IRANIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA

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SABERI HAZHER; PEZESHKI MODARRES MEHDI; NASIRI TUSI MOHSEN; FORUTAN HOSSEIN

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Journal: GOVARESH JOURNAL Year:2013 | Volume:18 | Issue:1 (82) Page(s): 21-27

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Title

RESULTS OF TRANSARTERIAL CHEMOEMBOLIZATION (TACE) IN A GROUP OF IRANIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA

Author(s)

SABERI HAZHER | PEZESHKI MODARRES MEHDI | NASIRI TUSI MOHSEN | FORUTAN HOSSEIN | Issue Writer Certificate

Keywords

HCC (HEPATOCELLULAR CARCINOMA)Q2

TACE (TRANSARTERIAL CHEMOEMBOLIZATION)Q2

ASCITESQ3

THROMBOSISQ2

Abstract

Background: Hepatocellular carcinoma (HCC) is a primary liver cancer that frequently causes mortalities. Transarterial chemoembolization (TACE) is a new palliative treatment for advanced stages of HCC. In this study, we have assessed the results of TACE on a group of Iranian patients with advanced HCC treated at Imam Khomeini General Hospital.Materials and Methods: This was a case series, cohort study conducted on 36 patients with HCC who met the study criteria. Patients underwent two sessions of TACE at a 4-6 week interval. All patients underwent triphasic computerized scans (CT scan) before treatment and at six weeks after the second session.Results: After at least a one year follow up period, 20 (55.6%) patients died and 16 (41.7%) survived. Survival at 6 months was 58% and at 12 months, it was 33.3%. Post-TACE tumor necrosis (>50%) was significantly associated with 6 (p=0.029) and 12 (p=0.00) month survival. There was a significant association between 6 and 12 month survival and Okuda stage (p -V=0.001 and 0.003), ASCITES (p -V=0.058 and 0.012) and branch portal vein THROMBOSIS (p -V=0.036 and 0.024). There was no association of WHO criteria to 6 (p -V=0.139) and 12 (p -V=0.139) month survival.Conclusion: Tumor necrosis less than 50%, presence of ASCITES and THROMBOSIS of the portal branches are associated with lower survival. Suitable selection and taking into consideration post-TACE tumor necrosis is suggested to enhance survival.

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APA: Copy

SABERI, HAZHER, PEZESHKI MODARRES, MEHDI, NASIRI TUSI, MOHSEN, & FORUTAN, HOSSEIN. (2013). RESULTS OF TRANSARTERIAL CHEMOEMBOLIZATION (TACE) IN A GROUP OF IRANIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA. GOVARESH JOURNAL, 18(1 (82)), 21-27. SID. https://sid.ir/paper/86177/en

Vancouver: Copy

SABERI HAZHER, PEZESHKI MODARRES MEHDI, NASIRI TUSI MOHSEN, FORUTAN HOSSEIN. RESULTS OF TRANSARTERIAL CHEMOEMBOLIZATION (TACE) IN A GROUP OF IRANIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA. GOVARESH JOURNAL[Internet]. 2013;18(1 (82)):21-27. Available from: https://sid.ir/paper/86177/en

IEEE: Copy

HAZHER SABERI, MEHDI PEZESHKI MODARRES, MOHSEN NASIRI TUSI, and HOSSEIN FORUTAN, “RESULTS OF TRANSARTERIAL CHEMOEMBOLIZATION (TACE) IN A GROUP OF IRANIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA,” GOVARESH JOURNAL, vol. 18, no. 1 (82), pp. 21–27, 2013, [Online]. Available: https://sid.ir/paper/86177/en

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