A CORRELATION STUDY ON THE SUBIECTIVE CRITERIA VERSUS LOWER ESOPHAGEAL SPHINCTER PRESSURE IN IDIOPATHIC ACHALASIA

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YAGHOUBI M.; MIKAEILI J.; MONTAZERI GH.; NOURI N.; SOHRABI MASOUD REZA; MALEKZADEH R.

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Journal: GOVARESH JOURNAL Year:2001 | Volume:5 | Issue:29-30 Page(s): 148-153

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Title

A CORRELATION STUDY ON THE SUBIECTIVE CRITERIA VERSUS LOWER ESOPHAGEAL SPHINCTER PRESSURE IN IDIOPATHIC ACHALASIA

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Keywords

ACHALASIAQ3

LOWER ESOPHAGEAL SPHINCTERQ4

PRESSUREQ3

SYMPTOM SCOREQ3

Abstract

Background: ACHALASIA is an esophageal motor disorder characterized with aperistalsis and incomplete relaxation of the LOWER ESOPHAGEAL SPHINCTER (LES). Previous studies showing the meaningful agreement between LES PRESSURE and the severity of clinical symptoms arc scanty. Aims: To assess correlation between the clinical scoring and the LES PRESSURE as well as determining whether the clinical severity score can predict LES PRESSURE in patients with idiopathic ACHALASIA. Methods: Over a period of 4 years from 1997 to 2001 all consenting symptomatic and newly diagnosed patients with idiopathic ACHALASIA were consecutively enrolled. Final diagnosis was established based on clinical, radiographic, endoscopic and manometric criteria. The severity of five cardinal symptoms as scored on a scale of 0 to 3 and each patient acquired a total score of 1 to 15. Then manometry was performed and the mean of five complete pull through measurements was recorded as the resting LES press Lire.Results: 115 patients with a mean age of 37.7 (12-90) years (67 men and 48 women) were included in the study. Mean total score was 9.32 (3.0-14.0) and mean LES PRESSURE before therapy was 56.2 (8.0-107.8) mmHg. Linear Regression Analysis showed a significant predicting ability of total score for the LES PRESSURE (P value<0.002, r=0.290). Female gender, age less than or equal to 40 and the duration of symptoms less than or equal to 2.00 appears to be the most important predicting factors or the correlation.Conclusion: Our study showed that clinical score can be an appropriate predictor of the LES PRESSURE in patients with idiopathic ACHALASIA using of our scoring system. There is a need for further studies to evaluate similar correlation after therapeutic intervention.

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APA: Copy

YAGHOUBI, M., MIKAEILI, J., MONTAZERI, GH., NOURI, N., SOHRABI, MASOUD REZA, & MALEKZADEH, R.. (2001). A CORRELATION STUDY ON THE SUBIECTIVE CRITERIA VERSUS LOWER ESOPHAGEAL SPHINCTER PRESSURE IN IDIOPATHIC ACHALASIA. GOVARESH JOURNAL, 5(29-30), 148-153. SID. https://sid.ir/paper/86277/en

Vancouver: Copy

YAGHOUBI M., MIKAEILI J., MONTAZERI GH., NOURI N., SOHRABI MASOUD REZA, MALEKZADEH R.. A CORRELATION STUDY ON THE SUBIECTIVE CRITERIA VERSUS LOWER ESOPHAGEAL SPHINCTER PRESSURE IN IDIOPATHIC ACHALASIA. GOVARESH JOURNAL[Internet]. 2001;5(29-30):148-153. Available from: https://sid.ir/paper/86277/en

IEEE: Copy

M. YAGHOUBI, J. MIKAEILI, GH. MONTAZERI, N. NOURI, MASOUD REZA SOHRABI, and R. MALEKZADEH, “A CORRELATION STUDY ON THE SUBIECTIVE CRITERIA VERSUS LOWER ESOPHAGEAL SPHINCTER PRESSURE IN IDIOPATHIC ACHALASIA,” GOVARESH JOURNAL, vol. 5, no. 29-30, pp. 148–153, 2001, [Online]. Available: https://sid.ir/paper/86277/en

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