CELIAC DISEASE IN GONBAD-KAVOOS

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KHOSHNIAT M.; POURSHAMS A.; MOHAMMAD KHANI ASHRAF; TAVANGAR S.M.; SHAHBAZKHANI B.; MALEKZADEH R.

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Journal: GOVARESH JOURNAL Year:2005 | Volume:10 | Issue:3 (SN 52) Page(s): 131-133

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Title

CELIAC DISEASE IN GONBAD-KAVOOS

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Keywords

CELIAC DISEASEQ2

GLUTEN SENSITIVE ENTEROPATHYQ4

ESOPHAGEAL CANCERQ4

PREVALENCEQ3

IRANQ2

Abstract

Background: Northeast IRAN has one of the highest rates of ESOPHAGEAL CANCER in the world which is mainly squamous cell carcinoma (E SCC). CELIAC DISEASE (CD) has been identified as a risk factor for ESCC. The aim of this study is to determine the PREVALENCE of CD in Gonbad at northeast IRAN and probable relation between celiac and ESCC.Materials and Methods: fourteen hundred inhabitants of north eastern IRAN were randomly selected. The subjects underwent blood sampling for determination of IgA antibodies against tissue transglutaminase (anti- TTG). Subjects with positive anti-TTG underwent an interview, upper endoscopy and duodenal biopsy. The duodenal biopsies were classified according to Marsh criteria.Results: A total of 1209 subjects (female: 699) with mean age of 50±11.7 years were studied. Twelve subjects (female: 9) had a positive anti-TTG (1%). Four patients did not accept endoscopy. Eight cases underwent endoscopy and duodenal biopsy. Four, two and two subjects had Marsh III, II and I respectively. Flatulence and diarrhea (the most symptoms) were in five and four subjects and characteristic skin manifestation was reported in three subjects. One subject was already diagnosed as CD.Conclusions: although PREVALENCE of ESCC in northeast IRAN is significantly higher than central IRAN, the PREVALENCE of GLUTEN SENSITIVE ENTEROPATHY is the same (1%). It dose not appear that CD has any impact on the PREVALENCE of ESCC in IRAN.

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APA: Copy

KHOSHNIAT, M., POURSHAMS, A., MOHAMMAD KHANI, ASHRAF, TAVANGAR, S.M., SHAHBAZKHANI, B., & MALEKZADEH, R.. (2005). CELIAC DISEASE IN GONBAD-KAVOOS. GOVARESH JOURNAL, 10(3 (SN 52)), 131-133. SID. https://sid.ir/paper/86304/en

Vancouver: Copy

KHOSHNIAT M., POURSHAMS A., MOHAMMAD KHANI ASHRAF, TAVANGAR S.M., SHAHBAZKHANI B., MALEKZADEH R.. CELIAC DISEASE IN GONBAD-KAVOOS. GOVARESH JOURNAL[Internet]. 2005;10(3 (SN 52)):131-133. Available from: https://sid.ir/paper/86304/en

IEEE: Copy

M. KHOSHNIAT, A. POURSHAMS, ASHRAF MOHAMMAD KHANI, S.M. TAVANGAR, B. SHAHBAZKHANI, and R. MALEKZADEH, “CELIAC DISEASE IN GONBAD-KAVOOS,” GOVARESH JOURNAL, vol. 10, no. 3 (SN 52), pp. 131–133, 2005, [Online]. Available: https://sid.ir/paper/86304/en

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