COMPRESSION OF RISPERIDONE AND OLANZAPINE IN BEHAVIORAL DISTURBANCES OF ALZHEIMER: A RANDOMIZED DOUBLE BLIND CLINICAL TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOKHBER N.; AZARPAZHOUH M.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH Year:2007 | Volume:9 | Issue:33-34 Page(s): 33-42

Download Full-Text

Persian Verion

View:

15,756

Download:

Cites:

Information Journal Paper

Title

COMPRESSION OF RISPERIDONE AND OLANZAPINE IN BEHAVIORAL DISTURBANCES OF ALZHEIMER: A RANDOMIZED DOUBLE BLIND CLINICAL TRIAL

Author(s)

MOKHBER N. | AZARPAZHOUH M.R. | Issue Writer Certificate

Keywords

RISPERIDONEQ3

OLANZAPINEQ3

ANTIPSYCHOTICQ3

BEHAVIORAL DISTURBANCESQ2

ALZHEIMERQ3

DEMENTIAQ3

Abstract

Introduction: There are some doubts about therapeutic effects of OLANZAPINE and RISPERIDONE two ANTIPSYCHOTIC drugs on BEHAVIORAL DISTURBANCES in patients with ALZHEIMER's disease and concerns about safety have emerged. We assessed the effectiveness of these two atypical ANTIPSYCHOTIC drugs in outpatients with ALZHEIMER's disease. Methods and Materials: In this double-blind trial, 69 outpatients with ALZHEIMER's disease and psychosis, aggression, or agitation were randomly assigned to receive OLANZAPINE (dose, 2.5- 7.5 mg per day) or RISPERIDONE (dose, 0.5-4.5 mg per day). Patients were followed for up to 10 weeks. The main outcomes were the scores of the Clinical Global Impression of Change (CGI) scale and Brief Psychiatric Rating Scale (BPRS).Results: There were no significant differences among treatments with regard to improvement in RISPERIDONE and OLANZAPINE group on the CGI (3.2±4.3 vs. 3.5±5.8 & P Value=0.564) and BPRS scale (8.2±9.2.vs. 8.8±9.2 & P Value = 0.522) .Furthermore, although the number of patients who had left the study cause of side effects, was greater in RISPERIDONE group, sedation and headache are more common with OLANZAPINE than RISPERIDONE.Conclusion: Both RISPERIDONE and OLANZAPINE might be useful and reasonable treatment for patients who suffering from BEHAVIORAL DISTURBANCES due to psychosis in ALZHEIMER disease.

Cites

No record.

References

No record.

Cite

APA: Copy

MOKHBER, N., & AZARPAZHOUH, M.R.. (2007). COMPRESSION OF RISPERIDONE AND OLANZAPINE IN BEHAVIORAL DISTURBANCES OF ALZHEIMER: A RANDOMIZED DOUBLE BLIND CLINICAL TRIAL. JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH, 9(33-34), 33-42. SID. https://sid.ir/paper/88430/en

Vancouver: Copy

MOKHBER N., AZARPAZHOUH M.R.. COMPRESSION OF RISPERIDONE AND OLANZAPINE IN BEHAVIORAL DISTURBANCES OF ALZHEIMER: A RANDOMIZED DOUBLE BLIND CLINICAL TRIAL. JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH[Internet]. 2007;9(33-34):33-42. Available from: https://sid.ir/paper/88430/en

IEEE: Copy

N. MOKHBER, and M.R. AZARPAZHOUH, “COMPRESSION OF RISPERIDONE AND OLANZAPINE IN BEHAVIORAL DISTURBANCES OF ALZHEIMER: A RANDOMIZED DOUBLE BLIND CLINICAL TRIAL,” JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH, vol. 9, no. 33-34, pp. 33–42, 2007, [Online]. Available: https://sid.ir/paper/88430/en

Related Journal Papers