IMPACTS OF TREATMENT MANAGEMENT METHODS ON CONTROL OF TOXICITY AND SIDE EFFECTS OF CHEMOTHERAPY REGIMENS IN BREAST CANCER

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HATAM N.; BASTANI P.; AHMADLOO N.; AHMADKIA DALIRI A.A.; SADEGHI FAR J.

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Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2012 | Volume:20 | Issue:1 Page(s): 42-50

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Title

IMPACTS OF TREATMENT MANAGEMENT METHODS ON CONTROL OF TOXICITY AND SIDE EFFECTS OF CHEMOTHERAPY REGIMENS IN BREAST CANCER

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Keywords

TOXICITY-ADJUVANT THERAPYQ2

BREAST CANCERQ2

SIDE EFFECTSQ2

Abstract

Introduction: Specific effects of chemotherapy regimens and their side-effects considerably influence on patients lives and their desires of accepting or rejecting therapies. It is obvious that the patient's idea about the effectiveness of therapy process and accepting the treatment by the patient can facilitate the recovery process greatly. In this study, the SIDE EFFECTS and toxicity of Docetaxel-Adriamicine-Cyclophosphamide (TAC) and Adriamicine-Cyclophosphamide- 5 FU (FAC) as two chemotherapy regimens were investigated.Materials & Methods: This investigation was done on a cohort of 100 patients suffering from BREAST CANCER with node positive being treated with TAC or FAC as a double blind study. Data was gathered by completing special check-lists as interviews at the last session of chemotherapy and surveying the patients' medical records. Data was analyzed by relevant statistical tests such as Independent T-test.Findings: The results showed that in most the aspects such as amenorrhea, anemia, febrile neutropenia, hyper pigmentation and nail disorder, neurologic toxicity, convulsion, nomeness and edema, the average mean was higher in TAC arm statistically significant.Discussion & Conclusion: Applying treatment managing approaches tend more to emphasize on patient’s education and improving their knowledge before starting chemotherapy cycle, convening of compulsory consult meetings with expert psychiatrists and psychologists and establishing supportive groups by patients who have recovered from cancer can lead to better and more conscious encountering for such patients and help them accept the therapy more conveniently.

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APA: Copy

HATAM, N., BASTANI, P., AHMADLOO, N., AHMADKIA DALIRI, A.A., & SADEGHI FAR, J.. (2012). IMPACTS OF TREATMENT MANAGEMENT METHODS ON CONTROL OF TOXICITY AND SIDE EFFECTS OF CHEMOTHERAPY REGIMENS IN BREAST CANCER. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 20(1), 42-50. SID. https://sid.ir/paper/90226/en

Vancouver: Copy

HATAM N., BASTANI P., AHMADLOO N., AHMADKIA DALIRI A.A., SADEGHI FAR J.. IMPACTS OF TREATMENT MANAGEMENT METHODS ON CONTROL OF TOXICITY AND SIDE EFFECTS OF CHEMOTHERAPY REGIMENS IN BREAST CANCER. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;20(1):42-50. Available from: https://sid.ir/paper/90226/en

IEEE: Copy

N. HATAM, P. BASTANI, N. AHMADLOO, A.A. AHMADKIA DALIRI, and J. SADEGHI FAR, “IMPACTS OF TREATMENT MANAGEMENT METHODS ON CONTROL OF TOXICITY AND SIDE EFFECTS OF CHEMOTHERAPY REGIMENS IN BREAST CANCER,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 20, no. 1, pp. 42–50, 2012, [Online]. Available: https://sid.ir/paper/90226/en

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