مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

ISOLATION AND IDENTIFICATION OF STRAINS OF IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA STRAINS ISOLATED IN CLINICAL SAMPLES FROM 4 MAJOR HOSPITALS OF TEHRAN, USING MIC METHOD

Pages

  159-168

Abstract

 Introduction: PSEUDOMONAS AERUGINOSA is a major agent of hospital infection which has a resistance intrinsic to a wide range of Antibiotics. It is resistant to beta-lactam antibiotics because of Beta-lactamase and Metalo-lactamase enzymes production. They have crucial problems in the treatment. The goal of this research is to isolate and characterize strains which are resistant to beta-lactam and IMIPENEM Antibiotics in clinical samples from four major hospitals in TehranMethods & methods: In this study 600 samples of PSEUDOMONAS AERUGINOSA were collected from patients and those people referring to Baqyiatallah hospital , Imam Khomeini hospital , Shahid Motahari Burns Center and Pediatrics Center during two years, In the first step Antibacterial resistance were prefer by wide range of Antibiotics (Kirby-Bauar). The MIC test was used to Ceftazidime and IMIPENEM by MICrodiution tube and CLSI protocol.Findings: This research demonstrated that the highest sensitivity of bacteria is to IMIPENEM (92%) and Tetracycline (91.2%) The results showed that 6 % of the MIC of strains are resistant to IMIPENEM (4μg/ml≤MIC) and the 39.5 % of them are resistant to Ceftazidime (16μg/ml≤MIC), respectively.Discussion & conclusions: These results showed that consumption of these Antibiotics should be used precisely due to the highest resistance of these bacteria to IMIPENEM and third generation Cephalosporin’s otherwise it can transfer to other strains Gram-Negative bacteria special.

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    APA: Copy

    BAGHERI, O.A.B., OLAD, G., SHAHECHERAGHI, F., & SARVARI, R.. (2017). ISOLATION AND IDENTIFICATION OF STRAINS OF IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA STRAINS ISOLATED IN CLINICAL SAMPLES FROM 4 MAJOR HOSPITALS OF TEHRAN, USING MIC METHOD. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 24(6), 159-168. SID. https://sid.ir/paper/90351/en

    Vancouver: Copy

    BAGHERI O.A.B., OLAD G., SHAHECHERAGHI F., SARVARI R.. ISOLATION AND IDENTIFICATION OF STRAINS OF IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA STRAINS ISOLATED IN CLINICAL SAMPLES FROM 4 MAJOR HOSPITALS OF TEHRAN, USING MIC METHOD. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;24(6):159-168. Available from: https://sid.ir/paper/90351/en

    IEEE: Copy

    O.A.B. BAGHERI, G. OLAD, F. SHAHECHERAGHI, and R. SARVARI, “ISOLATION AND IDENTIFICATION OF STRAINS OF IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA STRAINS ISOLATED IN CLINICAL SAMPLES FROM 4 MAJOR HOSPITALS OF TEHRAN, USING MIC METHOD,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 6, pp. 159–168, 2017, [Online]. Available: https://sid.ir/paper/90351/en

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