Effects of Cuminum cyminum Essence on Rat Ovary Function following Administration of Dopaminergic Agonist and Antagonist

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Bina L.; NAJAFZADE VARZI H.; FATEMI TABATABAEI R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2018 | Volume:26 | Issue:1 Page(s): 13-22

Download Full-Text

Persian Verion

View:

547

Download:

Cites:

Information Journal Paper

Title

Effects of Cuminum cyminum Essence on Rat Ovary Function following Administration of Dopaminergic Agonist and Antagonist

Author(s)

Bina L. | NAJAFZADE VARZI H. | FATEMI TABATABAEI R. | Issue Writer Certificate

Keywords

oestrogenQ1

progesteroneQ1

bromocriptinQ1

metoclopramideQ1

cuminum cyminumQ1

ovaryQ2

ratQ1

Abstract

Introduction: Considering the application of medicinal plants in treatment of endocrine diseases including ovarian function and also regarding the estrogenic properties of cumin (cuminum cyminum), the present study aimed at evaluating effects of cumin essence on oestrogen, progesterone, and ovarian follicles changes in rat at presence or absence of dopaminergic agonist and antagonist. Materials & methods: In this experimental and animal model study, 35 female rats were divided into 7 groups which received normal saline (IP), metoclopramide (90mg/kg-IP), bromocriptin (4mg/kg-SC), metoclopramide and bromocriptin, metoclopramide and cumin (4mg/kg-PO), cumin, bromocriptin, and cumin for 10 days, respectively. Then, the rats were anesthetised with chloroform and their heart blood was collected for oestrogen and progesterone assessment. Afterward, ovaries and uterines were removed and weighted and the immature and mature follicles were counted. Findings: The results showed that metoclopramide decreases oestrogen and progesterone concentration and bromocriptin administration can reverse its effect. On the other hand, cumin application proved to decrease the weight of the rats and serum oestrogen concentration. Coadministration of cumin and bromocriptin increased oestrogen concentration and the numbers of folliculars. Discussion & conclusions: Cumin usage can accelerate the effects of bromocriptin as a dopaminergic on ovarian function.

Cites

Antidepressant-like effect of Cuminum cyminum essential oil on the forced swim and tail suspension tests in male mice

References

No record.

Cite

APA: Copy

Bina, L., NAJAFZADE VARZI, H., & FATEMI TABATABAEI, R.. (2018). Effects of Cuminum cyminum Essence on Rat Ovary Function following Administration of Dopaminergic Agonist and Antagonist. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 26(1 ), 13-22. SID. https://sid.ir/paper/90446/en

Vancouver: Copy

Bina L., NAJAFZADE VARZI H., FATEMI TABATABAEI R.. Effects of Cuminum cyminum Essence on Rat Ovary Function following Administration of Dopaminergic Agonist and Antagonist. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;26(1 ):13-22. Available from: https://sid.ir/paper/90446/en

IEEE: Copy

L. Bina, H. NAJAFZADE VARZI, and R. FATEMI TABATABAEI, “Effects of Cuminum cyminum Essence on Rat Ovary Function following Administration of Dopaminergic Agonist and Antagonist,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 1 , pp. 13–22, 2018, [Online]. Available: https://sid.ir/paper/90446/en

Related Journal Papers