EFFECT OF INTRAVENOUS AND INTRA-CUFF HYDROCORTISONE ON THE FREQUENCY AND SEVERITY OF COUGHS AFTER ENDOTRACHEAL TUBE INSERTION: A RANDOMIZED‐CONTROLLED TRIAL

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YOUSEFI ABBASALI; BAGHERI HOSSEIN; NOURIAN JAVAD; KHOSRAVI AHMAD; KHATIBI MOHAMMAD REZA

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Journal: Avicenna Journal of Nursing and Midwifery Care Year:2017 | Volume:25 | Issue:3 Page(s): 1-7

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Title

EFFECT OF INTRAVENOUS AND INTRA-CUFF HYDROCORTISONE ON THE FREQUENCY AND SEVERITY OF COUGHS AFTER ENDOTRACHEAL TUBE INSERTION: A RANDOMIZED‐CONTROLLED TRIAL

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Keywords

ENDOTRACHEAL INTUBATIONQ2

COUGHQ2

INTRAVENOUS HYDROCORTISONEQ2

INTRA-CUFF HYDROCORTISONEQ2

Abstract

Introduction: COUGH is a common complication after anesthesia and can lead to serious complications. This study was carried out to evaluate the effect of intravenous and intracuff hydrocortisone on the severity of COUGH after anesthesia using an endotracheal tube.Methods: In this RCT study, 135 patients were selected and randomly assigned to groups A, B and, C group. After intubation, in group A, 100 mg of diluted hydrocortisone with 5 mL of distilled water was injected Intravenously (IV) in group B; the endotracheal tube cuff was filled with 100 mg of hydrocortisone and for group C, the cuff was filled by 5 to 10 mL of distilled water. Frequency and severity of COUGH using VAS at 2, 6, and 24 hours after anesthesia was measured.Results: No significant difference was revealed in the frequency of COUGH at 2, 6, and 24 hours after anesthesia in all 3 groups (P>0.05). In the group that received hydrocortisone intravenously, at 2 and 6 hours after anesthesia, equal frequency of COUGH (4.35%) and at 24 hours after anesthesia, reduced frequency of COUGH (2.17%) was observed compared with the control group. However, this decrease was not significant. In the cuff hydrocortisone group, at 2 hours after anesthesia, in the experimental group (6.67%) compared to the control group (6.82%) decreased frequency of COUGH, and at 6 hours after anesthesia in the experimental group (8.83%) compared to the control (4.55%) increased frequency of COUGH, and at 24 hours after anesthesia, the same frequency of COUGH (0%) was observed. However, this change was not significant.Conclusions: Using INTRAVENOUS HYDROCORTISONE and INTRA-CUFF HYDROCORTISONE there was no significant benefit in reducing frequency of COUGH, compared to the control group.

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APA: Copy

YOUSEFI, ABBASALI, BAGHERI, HOSSEIN, NOURIAN, JAVAD, KHOSRAVI, AHMAD, & KHATIBI, MOHAMMAD REZA. (2017). EFFECT OF INTRAVENOUS AND INTRA-CUFF HYDROCORTISONE ON THE FREQUENCY AND SEVERITY OF COUGHS AFTER ENDOTRACHEAL TUBE INSERTION: A RANDOMIZED?CONTROLLED TRIAL. AVICENNA JOURNAL OF NURSING AND MIDWIFERY CARE (SCIENTIFIC JOURNAL OF HAMADAN NURSING & MIDWIFERY FACULTY), 25(3), 1-7. SID. https://sid.ir/paper/92576/en

Vancouver: Copy

YOUSEFI ABBASALI, BAGHERI HOSSEIN, NOURIAN JAVAD, KHOSRAVI AHMAD, KHATIBI MOHAMMAD REZA. EFFECT OF INTRAVENOUS AND INTRA-CUFF HYDROCORTISONE ON THE FREQUENCY AND SEVERITY OF COUGHS AFTER ENDOTRACHEAL TUBE INSERTION: A RANDOMIZED?CONTROLLED TRIAL. AVICENNA JOURNAL OF NURSING AND MIDWIFERY CARE (SCIENTIFIC JOURNAL OF HAMADAN NURSING & MIDWIFERY FACULTY)[Internet]. 2017;25(3):1-7. Available from: https://sid.ir/paper/92576/en

IEEE: Copy

ABBASALI YOUSEFI, HOSSEIN BAGHERI, JAVAD NOURIAN, AHMAD KHOSRAVI, and MOHAMMAD REZA KHATIBI, “EFFECT OF INTRAVENOUS AND INTRA-CUFF HYDROCORTISONE ON THE FREQUENCY AND SEVERITY OF COUGHS AFTER ENDOTRACHEAL TUBE INSERTION: A RANDOMIZED?CONTROLLED TRIAL,” AVICENNA JOURNAL OF NURSING AND MIDWIFERY CARE (SCIENTIFIC JOURNAL OF HAMADAN NURSING & MIDWIFERY FACULTY), vol. 25, no. 3, pp. 1–7, 2017, [Online]. Available: https://sid.ir/paper/92576/en

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