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Information Journal Paper

Title

Management of Hospitalized Adult Patients with Coronavirus 2019 (COVID-19): A Therapeutic Guideline

Pages

  111-118

Abstract

 Introduction: COVID-19, caused by the SARS-CoV-2 s train, is highly contagious and can be fatal in acute cases. In severe cases, hypoxia leads to hypoxemia. In these conditions, oxygen management using ventilation and intubation is very necessary. Optimizing and s tandardizing treatment management through clinical data can improve the quality of care as well as the patient’ s condition. Materials and Methods: In this s tudy, using data from randomized clinical trials and sys tematic review and meta-analysis, several critical PICOs (population, intervention, comparator, and outcome) were collected. The GRADE approach was also used to evaluate the quality of evidence and the effectiveness of the recommendations derived from the s tudies. Results: Based on the available evidence, the following recommendations advised to improve the condition of patients: I) the use of sys temic corticos teroids in patients who need oxygen and the use of anticoagulant drugs during hospitalization recommended. II) Treatment of monoclonal antibody (i. e., interleukin-6-receptor antagonis t) with oxygen is conditionally recommended in patients with respiratory failure. III) The hydroxychloroquine in combination with lopinavir-ritonavir should not be used in patients with respiratory failure. IV) The use of azithromycin, hydroxychloroquine in combination with azithromycin, colchicine, and remdesivir are recommended temporarily in patients with ventilation. V) Early diagnosis and initiation of treatment have a significant effect on the patient’ s recovery. Conclusion: The proposed guideline obtained from the evaluation of clinical trials, sys tematic reviews, and meta-analyses can improve the outcomes of patients with COVID-19 disease.

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    APA: Copy

    KOLIVAND, PIRHOSSEIN, DEHESTANI, VAHID, & KAZEMI, HADI. (2021). Management of Hospitalized Adult Patients with Coronavirus 2019 (COVID-19): A Therapeutic Guideline. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 9(2 ), 111-118. SID. https://sid.ir/paper/950199/en

    Vancouver: Copy

    KOLIVAND PIRHOSSEIN, DEHESTANI VAHID, KAZEMI HADI. Management of Hospitalized Adult Patients with Coronavirus 2019 (COVID-19): A Therapeutic Guideline. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM[Internet]. 2021;9(2 ):111-118. Available from: https://sid.ir/paper/950199/en

    IEEE: Copy

    PIRHOSSEIN KOLIVAND, VAHID DEHESTANI, and HADI KAZEMI, “Management of Hospitalized Adult Patients with Coronavirus 2019 (COVID-19): A Therapeutic Guideline,” NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, vol. 9, no. 2 , pp. 111–118, 2021, [Online]. Available: https://sid.ir/paper/950199/en

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