COMPARISON BETWEEN FENTANYL AND SUFENTANIL ANALGESIC EFFECT ON SPINAL ANESTHESIA

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ABBASNEZHAD A.A.; JALILI MOHAMMAD REZA; TALAEI ALI REZA; SAEIDI HOSSEIN

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Journal: Journal of Birjand University of Medical Sciences Year:2009 | Volume:15 | Issue:4 (37) Page(s): 19-26

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Title

COMPARISON BETWEEN FENTANYL AND SUFENTANIL ANALGESIC EFFECT ON SPINAL ANESTHESIA

Author(s)

ABBASNEZHAD A.A. | JALILI MOHAMMAD REZA | TALAEI ALI REZA | SAEIDI HOSSEIN | Issue Writer Certificate

Keywords

ANALGESIAQ3

FENTANYLQ3

SUFENTANILQ3

SPINAL ANESTHESIAQ2

Abstract

Background and Aim: One of the main objectives of anesthesia is “loss of ability to feel pain (ANALGESIA) and there are different methods and drugs to acquire this. SPINAL ANESTHESIA with lidocaine 5% is a method of causing ANALGESIA whose period is about 60 minutes. Since lengthier ANALGESIA is required in some surgeries and using opiates is one of the methods to prolong anesthesia, in this research SUFENTANIL and FENTANYL were used in SPINAL ANESTHESIA to discover which a more effective drug is.Materials and Methods: In this clinical trial study 80 men aged between 50 and 60 years who had been hospitalized in Gonabad Panzdeh-e-khordad hospital in 2006, for inguinal hernia operation. The patients were randomly divided into two equal groups of 40 each. In one group (F) 20mg FENTANYL with 100mg lidocaine 5% and in the other group (S) one 5mg SUFENTANIL together with the same dose of lidocaine was used for SPINAL ANESTHESIA. A check-list and a questionnaire were used to record the necessary data. The obtained data was analyzed by means of SPSS software using statistical t-test, and P<0.05 was taken as the significant level.Results: Mean of ANALGESIA period in group F was 99.37±18.61 minutes and in group S it was 153.62±26.62 minutes, so there was a significant difference between the two groups regarding the period of ANALGESIA (P<0.001). In group F the occurance of hypotention was %37.5, bradycardia %27.5 ,and nausea and vomiting was %10, but in group S they were %40, %32.5, and %15 respectively. The difference was not statistically significant.Conclusion: Regarding the results of this study, ANALGESIA in SPINAL ANESTHESIA with SUFENTANIL was lengthier than ANALGESIA caused by FENTANYL, and there was a significant difference between the effects of the two drugs (P<0.001). But it was not significant differences on hypotention, bradycardia, and nausea and vomiting so it is recommended to use SUFENTANIL instead of FENTANYL in SPINAL ANESTHESIA if ANALGESIA for more than100 minutes is required.

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APA: Copy

ABBASNEZHAD, A.A., JALILI, MOHAMMAD REZA, TALAEI, ALI REZA, & SAEIDI, HOSSEIN. (2009). COMPARISON BETWEEN FENTANYL AND SUFENTANIL ANALGESIC EFFECT ON SPINAL ANESTHESIA. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 15(4 (37)), 19-26. SID. https://sid.ir/paper/95380/en

Vancouver: Copy

ABBASNEZHAD A.A., JALILI MOHAMMAD REZA, TALAEI ALI REZA, SAEIDI HOSSEIN. COMPARISON BETWEEN FENTANYL AND SUFENTANIL ANALGESIC EFFECT ON SPINAL ANESTHESIA. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;15(4 (37)):19-26. Available from: https://sid.ir/paper/95380/en

IEEE: Copy

A.A. ABBASNEZHAD, MOHAMMAD REZA JALILI, ALI REZA TALAEI, and HOSSEIN SAEIDI, “COMPARISON BETWEEN FENTANYL AND SUFENTANIL ANALGESIC EFFECT ON SPINAL ANESTHESIA,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 4 (37), pp. 19–26, 2009, [Online]. Available: https://sid.ir/paper/95380/en

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