THE EFFECT OF A SINGLE DOSE OF MORPHINE ON MUSCLE FATIGUE INDICES IN MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AMIRESMAILI SEDIGHEH; MOBINI MASSOUD; ROOHBAKHSH ALI; SHAMSIZADEH ALI; AMIN FATEMEH; ALLAHTAVAKOLI MOHAMMAD

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Birjand University of Medical Sciences Year:2016 | Volume:23 | Issue:3 Page(s): 190-197

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,123

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF A SINGLE DOSE OF MORPHINE ON MUSCLE FATIGUE INDICES IN MALE RATS

Author(s)

Keywords

MORPHINEQ3

MUSCLE FATIGUEQ2

LDHQ2

CPKQ2

Abstract

Background and Aim: Endogenous opioids and addictive opiate drugs change many body functions. . Previous studies have referred to the effects of MORPHINE on smooth and pulmonary muscles., but the effects of opioids on skeletal muscles is not known well. Thus, the current study aimed at assessing the effect of a single dose of MORPHINE on MUSCLE FATIGUE in male rats.Materials and Methods: In this experimental study, 40 male Wistar rats weighing 220-270 g were randomly divided into four equal groups: control (the mice were kept in their cages and received food and water), MORPHINE receiving group, fatigue group (the mice in this group were kept running on a treadmill. For 120 minutes at a rate of 20 meters per minute), and MORPHINE plus fatigue group. At the end of the experiments, blood samples were obtained from the corner of their eyes and were sent to the laboratory for measurement of MUSCLE FATIGUE indexes including lactate dehydrogenase (LDH) and creatine phosphokinase (CPK).Results: Administration of MORPHINE to the fatigue group decreased running time compared with the control group (P=0.009). Furthermore, administration of MORPHINE to the fatigue group significantly increased serum levels of LDH (P=0.009) and CPK (P=0.008).Conclusion: The present study showed that administration of a single dose of MORPHINE in rats increases MUSCLE FATIGUE biomarkers (LDH, CPK).

Cites

No record.

References

No record.

Cite

APA: Copy

AMIRESMAILI, SEDIGHEH, MOBINI, MASSOUD, ROOHBAKHSH, ALI, SHAMSIZADEH, ALI, AMIN, FATEMEH, & ALLAHTAVAKOLI, MOHAMMAD. (2016). THE EFFECT OF A SINGLE DOSE OF MORPHINE ON MUSCLE FATIGUE INDICES IN MALE RATS. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 23(3), 190-197. SID. https://sid.ir/paper/95590/en

Vancouver: Copy

AMIRESMAILI SEDIGHEH, MOBINI MASSOUD, ROOHBAKHSH ALI, SHAMSIZADEH ALI, AMIN FATEMEH, ALLAHTAVAKOLI MOHAMMAD. THE EFFECT OF A SINGLE DOSE OF MORPHINE ON MUSCLE FATIGUE INDICES IN MALE RATS. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;23(3):190-197. Available from: https://sid.ir/paper/95590/en

IEEE: Copy

SEDIGHEH AMIRESMAILI, MASSOUD MOBINI, ALI ROOHBAKHSH, ALI SHAMSIZADEH, FATEMEH AMIN, and MOHAMMAD ALLAHTAVAKOLI, “THE EFFECT OF A SINGLE DOSE OF MORPHINE ON MUSCLE FATIGUE INDICES IN MALE RATS,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 23, no. 3, pp. 190–197, 2016, [Online]. Available: https://sid.ir/paper/95590/en

Related Journal Papers