EFFECT OF AALCOHOLIC EXTRACT OF HOP FLOWERS ON SERUM LEVEL PITUITARY-THYROID HORMONES IN ADULT MALE RATS

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HOSSEINI SEYED EBRAHIM

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Journal: Journal of Birjand University of Medical Sciences Year:2015 | Volume:21 | Issue:4 Page(s): 425-431

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Title

EFFECT OF AALCOHOLIC EXTRACT OF HOP FLOWERS ON SERUM LEVEL PITUITARY-THYROID HORMONES IN ADULT MALE RATS

Author(s)

HOSSEINI SEYED EBRAHIM | Issue Writer Certificate

Keywords

HUMULUSQ2

THYROTROPINQ2

TRIIODOTHYRONINEQ2

THYROXINEQ3

RATSQ2

Abstract

Background and Aim: Hop with, scientific name of HUMULUS Lupulus, has got estrogenic, sedative, hypnotic, and antiseptic properties in the treatment of certain diseases. The present study aimed at assessing the effects of the herb on pituitary–thyroid hormones in adult male RATS.Materials and Methods: This experimental study was conducted on 45 adult male Wistar RATS. The RATS were divided into 5 equal groups including control (no treatment), control (saline) and three experimental groups receiving doses of the hop flower extract 50,100, and 150mg/kg gavage for 10 days, respectively. At the end of the tenth day., blood samples were derived from the RATS’ hearts and their blood hormone concentrations of THYROTROPIN (T3), THYROXINE (T4), and THYROTROPIN (THS) were measured by means of gamma counter. The obtained data was analysed employing SPSS software (V: 18) using Anova and Tukey. Statistical tests at the significant level P≤0.05.Results: It was found that the experimental groups receiving doses of 150 and 100 mg/kg, their serum hormone levels of T3, T4 and TSH levels significantly reduced (P≥0.05).Conclusion: The results showed that the ethanol extract of hop flowers with a flavonoid phytoestrogens reduce T4, T3 and TSH hormones.

Cites

THE EFFECTS OF (HUMULUS LUPULUS L.) HOPS ON MENOPAUSAL VASOMOTOR SYMPTOMS: A SYSTEMATIC REVIEW AND META- ANALYSIS

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APA: Copy

HOSSEINI, SEYED EBRAHIM. (2015). EFFECT OF AALCOHOLIC EXTRACT OF HOP FLOWERS ON SERUM LEVEL PITUITARY-THYROID HORMONES IN ADULT MALE RATS. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 21(4), 425-431. SID. https://sid.ir/paper/95665/en

Vancouver: Copy

HOSSEINI SEYED EBRAHIM. EFFECT OF AALCOHOLIC EXTRACT OF HOP FLOWERS ON SERUM LEVEL PITUITARY-THYROID HORMONES IN ADULT MALE RATS. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;21(4):425-431. Available from: https://sid.ir/paper/95665/en

IEEE: Copy

SEYED EBRAHIM HOSSEINI, “EFFECT OF AALCOHOLIC EXTRACT OF HOP FLOWERS ON SERUM LEVEL PITUITARY-THYROID HORMONES IN ADULT MALE RATS,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 4, pp. 425–431, 2015, [Online]. Available: https://sid.ir/paper/95665/en

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