PREVALENCE OF THE MINOR-Β THALASSEMIA IN BIRJAND CITY

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CHAHKANDI T.; SADAT JOU S.A.R.

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Paper Information

Journal: Journal of Birjand University of Medical Sciences Year:2001 | Volume:8 | Issue:1 (13) Page(s): 17-21

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Title

PREVALENCE OF THE MINOR-Β THALASSEMIA IN BIRJAND CITY

Author(s)

CHAHKANDI T. | SADAT JOU S.A.R. | Issue Writer Certificate

Keywords

MICROCYTOSISQ4

MINOR-Β THALASSEMIAQ4

HEMOGLOBIN A2Q4

Abstract

Introduction and aim: Thalassemia is the most prevalent hereditary anemia throughout the world. In Iran, there are about 25000 thalassemia cases, and every year about 1500 new thalassemia cases are born.This study aimed to determine prevalence of minor-B thalassemia in Birjand.Material and methods: In this cross-sectional study, 480 students (260 males, 220 females) who were randomly selected and CBC was done for all of them.Then, MICROCYTOSIS cases, after taking oral iron for a period of one month, were tested again; and those with unrelieved MICROCYTOSIS were assigned to undergo HEMOGLOBIN A2 electrophoresis. Cases proved above 3. 7% were diagnosed and recorded as thalassemia B cases.Results: From among 480 students, 34 (7.1%) suffered from MICROCYTOSIS; seven of whom were excluded from the study because they didn't take oral iron. After taking oral iron for one-month period, MICROCYTOSIS of 13 cases (2.7%) was relieved; from the remainder of 14 individuals, 5 cases (2 females and 3 males; 1% of the total) had HBA2 over 3.7%. (p=0.52).Conclusion: Considering the low prevalence of the mentioned gene in the region (1%) and the trivial success of the screening plan prior to marriage, it is recommended that screening plan be carried out at a different age level such as childhood or high school period.

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APA: Copy

CHAHKANDI, T., & SADAT JOU, S.A.R.. (2001). PREVALENCE OF THE MINOR-Β THALASSEMIA IN BIRJAND CITY. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 8(1 (13)), 17-21. SID. https://sid.ir/paper/95757/en

Vancouver: Copy

CHAHKANDI T., SADAT JOU S.A.R.. PREVALENCE OF THE MINOR-Β THALASSEMIA IN BIRJAND CITY. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2001;8(1 (13)):17-21. Available from: https://sid.ir/paper/95757/en

IEEE: Copy

T. CHAHKANDI, and S.A.R. SADAT JOU, “PREVALENCE OF THE MINOR-Β THALASSEMIA IN BIRJAND CITY,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 1 (13), pp. 17–21, 2001, [Online]. Available: https://sid.ir/paper/95757/en

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