RENAL TUBULAR FUNCTION IN CHILDREN SUFFERING FROM IRON DEFICIENCY ANEMIA

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ALAEI F.; MOHKAM M.; SHAMSIAN SH.; RAHNAVARDI M.; BIKDELI B.

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Journal: Annals of Military and Health Sciences Research Year:2007 | Volume:5 | Issue:1 (SERIAL NUMBER 17) Page(s): 1165-1169

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Title

RENAL TUBULAR FUNCTION IN CHILDREN SUFFERING FROM IRON DEFICIENCY ANEMIA

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Keywords

IRON DEFICIENCY ANEMIAQ4

PROTEIN LOSINGQ3

RENAL TUBULAR FUNCTIONQ3

Abstract

Background: IRON DEFICIENCY ANEMIA is the most prevalent blood disease during infancy and childhood and iron deficiency even in the absence anemia could negatively impress the growth and development. IRON DEFICIENCY ANEMIA causes the destruction of proximal tubules and extension of peritubular space, especially in the cortex of kidneys. Hypoxia is assumed as the main cause of these changes. According to some studies, treatment with supplemental iron has led to renal function reach it's normal level. We planned our study to to investigate the tubular function in children suffering from IRON DEFICIENCY ANEMIA in Mofid Children's Hospital.Material and Methods: We performed our descriptive cross sectional study on the children admitted in Mofid Children's Hospital for any reason and the same time suffering from IRON DEFICIENCY ANEMIA. Via continuous visits and census, 60 children aging between 3-60 month who met inclusion criteria, entered the study and investigated for probable defects in tubular reabsorption of Na,K,Ca, Phos and proteins. Collected data were analyzed by SPSS version 11.Results: 52(87%) patients who entered the study had at least one indicator of tubular dysfunction. While the most common tubulopathy was PROTEIN LOSING (65%), the most uncommon was impaired reabsorption of k+ (p<0.05). Among criterias for IRON DEFICIENCY ANEMIA, total iron binding capacity(TIBC) was higher in all patients with at least one tubular dysfunction in comparison with patients without such an impairment. The difference between groups was statically significant for defects in reabsorption of Na+, K+ and Phos. ions. Tubular PROTEIN LOSING was more prevalent in younger patients and defects in reabsorption of K+ ion, was more common in patients with lower weight.Conclusions: According to high prevalence rate of tubular dysfunctions among those children suffering from IRON DEFICIENCY ANEMIA and lower age and weight of these patients; to avoid renal dysfunctions, it is reasonable to start the treatment as soon as possible.

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APA: Copy

ALAEI, F., MOHKAM, M., SHAMSIAN, SH., RAHNAVARDI, M., & BIKDELI, B.. (2007). RENAL TUBULAR FUNCTION IN CHILDREN SUFFERING FROM IRON DEFICIENCY ANEMIA. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 5(1 (SERIAL NUMBER 17)), 1165-1169. SID. https://sid.ir/paper/96503/en

Vancouver: Copy

ALAEI F., MOHKAM M., SHAMSIAN SH., RAHNAVARDI M., BIKDELI B.. RENAL TUBULAR FUNCTION IN CHILDREN SUFFERING FROM IRON DEFICIENCY ANEMIA. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2007;5(1 (SERIAL NUMBER 17)):1165-1169. Available from: https://sid.ir/paper/96503/en

IEEE: Copy

F. ALAEI, M. MOHKAM, SH. SHAMSIAN, M. RAHNAVARDI, and B. BIKDELI, “RENAL TUBULAR FUNCTION IN CHILDREN SUFFERING FROM IRON DEFICIENCY ANEMIA,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 5, no. 1 (SERIAL NUMBER 17), pp. 1165–1169, 2007, [Online]. Available: https://sid.ir/paper/96503/en

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