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Information Journal Paper

Title

SURVIVAL ANALYSIS IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISORDERS IN 1979-2004

Pages

  1337-1340

Abstract

 Background: The PRIMARY IMMUNODEFICIENCY disorders (PID) are abnormalities in development and maturation of the IMMUNE SYSTEM and PI patients may experience frequent infections. They may have a significant limitation in their physical and psychological well-being secondary to their illness. The purpose of this study was to describe the SURVIVAL time of Iranian patients with PID over a period of 25 years.Materials and Methods: Four hundreds and forty six patients with definite diagnosis of PID (based on standard criteria and laboratory tests), attending Allergy and Immunology clinic in Children Medical Center Hospital, ranging in age from 8-18 Years old, were studied and followed. A questionnaire was filled for recording all necessary information.Results: The MEAN AGE of all patients (63.2% male and 36.8% female) was 8.66±13.01 years and overall SURVIVAL time was 47.81±1.42 years. 20% of patients were died before 25 years old but about 80% of PID patients could live at least 60 years. The mean SURVIVAL time in common variable immune deficiency was 42.76±3.23 year, in Bruton disease was 28.42±1.99 year, in Hyper IgM disease was 18.04±3.65year, in Chronic Granolomatose Disease was 51.77±1.93 year, in IgA deficiency disorder was 27.1±1.3 year and in SeverCombinedimmunedeficiencywas4.49±0.71 year.Conclusion: Diagnostic delay can result in high mortality and more complications in untreated patients and failure to provide therapy can be a cause of low SURVIVAL rate in PID patients. Therefore early diagnosis, good control and appropriate treatment will improve the SURVIVAL rate.

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    APA: Copy

    MOZAFARI, H., POURPAK, Z., & MOEIN, M.. (2007). SURVIVAL ANALYSIS IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISORDERS IN 1979-2004. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 5(3 (SERIAL NUMBER 19)), 1337-1340. SID. https://sid.ir/paper/96548/en

    Vancouver: Copy

    MOZAFARI H., POURPAK Z., MOEIN M.. SURVIVAL ANALYSIS IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISORDERS IN 1979-2004. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2007;5(3 (SERIAL NUMBER 19)):1337-1340. Available from: https://sid.ir/paper/96548/en

    IEEE: Copy

    H. MOZAFARI, Z. POURPAK, and M. MOEIN, “SURVIVAL ANALYSIS IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISORDERS IN 1979-2004,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 5, no. 3 (SERIAL NUMBER 19), pp. 1337–1340, 2007, [Online]. Available: https://sid.ir/paper/96548/en

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