THE COMPARISON OF INTRALUMINAL WITH INTRAVENOUS ADMINISTRATION OF VANCOMYCIN IN PERMANENT HAEMODIALYSIS CATHETER INFECTION ON THE RATE OF ITS TREATMENT AND CATHETER REMOVAL

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BEYGI A.A.; KHANSOLTANI S.; MASOUDPOUR H.; ESHAGHIAN A.

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Journal Paper

Paper Information

Journal: Annals of Military and Health Sciences Research Year:2008 | Volume:6 | Issue:2 (SERIAL NUMBER 22) Page(s): 141-145

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Title

THE COMPARISON OF INTRALUMINAL WITH INTRAVENOUS ADMINISTRATION OF VANCOMYCIN IN PERMANENT HAEMODIALYSIS CATHETER INFECTION ON THE RATE OF ITS TREATMENT AND CATHETER REMOVAL

Author(s)

BEYGI A.A. | KHANSOLTANI S. | MASOUDPOUR H. | ESHAGHIAN A. | Issue Writer Certificate

Keywords

END-STAGE RENAL DISEASE (ESRD)Q3

HAEMODIALYSIS (HD)Q3

PERMCATQ3

Abstract

Background: Patients who use PERMCATh permanent catheter as the vascular access for hemodialysis are occasionally confronted with catheter-related infections. PERMCATh infections can lead to catheter removal in Haemodialysis patients. Successful use of a ‘locked-in’ antibiotic has decreased catheter infections. This study evaluates the impact of the intraluminal vancomycin in comparison with intravenous antibiotic administration.Material & Methods: This experimental nonrandomized controlled study included 67 end stage renal disease patients enrolled for HD from 2005 to 2007 at our hospitals. The patient was studied in to 2 groups. In the first group (intervention group), vancomycin was injected via each lumen of PERMCATh, with IV Ceftriaxone for 7 days, and then oral antibiotics was administered according to the culture fore three weeks. If the culture was negative, Cefixime was administered. In the second group intravenous Vancomycin + intravenous Amikacin prescribed. In both groups, if the patients had it enough response after 72 hours, PERMCATh was removed. Our endpoint is to assessment of catheter removal.Results: Patients characteristics didn’t differ between 2 groups. Of 28 patients in group 1, 1 catheter removal, and of 39 patients in group2, 22 catheter removals were done. There is a significant reduction of catheter removal in the first group (p<0.001).Conclusions: This study has shown that administration of Vancomycin via PERMCATh is more effective than intravenous, and increase life time of catheter.

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APA: Copy

BEYGI, A.A., KHANSOLTANI, S., MASOUDPOUR, H., & ESHAGHIAN, A.. (2008). THE COMPARISON OF INTRALUMINAL WITH INTRAVENOUS ADMINISTRATION OF VANCOMYCIN IN PERMANENT HAEMODIALYSIS CATHETER INFECTION ON THE RATE OF ITS TREATMENT AND CATHETER REMOVAL. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 6(2 (SERIAL NUMBER 22)), 141-145. SID. https://sid.ir/paper/96608/en

Vancouver: Copy

BEYGI A.A., KHANSOLTANI S., MASOUDPOUR H., ESHAGHIAN A.. THE COMPARISON OF INTRALUMINAL WITH INTRAVENOUS ADMINISTRATION OF VANCOMYCIN IN PERMANENT HAEMODIALYSIS CATHETER INFECTION ON THE RATE OF ITS TREATMENT AND CATHETER REMOVAL. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2008;6(2 (SERIAL NUMBER 22)):141-145. Available from: https://sid.ir/paper/96608/en

IEEE: Copy

A.A. BEYGI, S. KHANSOLTANI, H. MASOUDPOUR, and A. ESHAGHIAN, “THE COMPARISON OF INTRALUMINAL WITH INTRAVENOUS ADMINISTRATION OF VANCOMYCIN IN PERMANENT HAEMODIALYSIS CATHETER INFECTION ON THE RATE OF ITS TREATMENT AND CATHETER REMOVAL,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 6, no. 2 (SERIAL NUMBER 22), pp. 141–145, 2008, [Online]. Available: https://sid.ir/paper/96608/en

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