CALCULATION AND COMPARISON OF HEART INTEGRAL DOSE IN THE TREATMENT OF ESOPHAGUS CANCER WITH THREE PHOTON ENERGIES & USING CT SIMULATION AND TREATMENT PLANNING SYSTEM

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NEDAIE H.; GHARAATI H.; ZAHEDI K.; KAZEMIAN A.

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Journal: IRANIAN JOURNAL OF MEDICAL PHYSICS Year:2005 | Volume:2 | Issue:7 Page(s): 77-84

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Title

CALCULATION AND COMPARISON OF HEART INTEGRAL DOSE IN THE TREATMENT OF ESOPHAGUS CANCER WITH THREE PHOTON ENERGIES & USING CT SIMULATION AND TREATMENT PLANNING SYSTEM

Author(s)

NEDAIE H. | GHARAATI H. | ZAHEDI K. | KAZEMIAN A. | Issue Writer Certificate

Keywords

RADIOTHERAPYQ4

INTEGRAL DOSEQ3

HEART DOSEQ4

TREATMENT PLANNINGQ4

Abstract

Introduction: Esophageal cancer is one of the most frequently occurring cancers in Iran and having a high incidence rate among other countries. RADIOTHERAPY is one of the three methods (surgery, RADIOTHERAPY and chemotherapy) for radical or palliative treatment of esophageal cancer. In this method of treatment, the organs such as heart and spinal cord are regarded as organs at risk (OAR) which their dose should be kept below the tolerance level.Different techniques have been used in conventional RADIOTHERAPY, among which two parallel opposed fields (POP) is used more often either for the whole course of the treatment or 2/3 of the fractions. In this technique, a great portion of the spinal cord may be involved in the treatment volume. The rate of treatment success may depend on the tolerance dose of heart and cord which act as the limiting factor.Materials and Methods: In this study, 10 patients with S.C.C. of esophagus having indication for external RADIOTHERAPY were selected. The CT scan simulations were performed for all the cases and their data were digitized to be used in computerized TREATMENT PLANNING system. TREATMENT PLANNING for three photon beam energies (Co-60, 6 and 10 MY) are obtained for each individual patient under the same geometry and dose. The INTEGRAL DOSE, absorbed dose and dose volume histogram (DVH) of the heart and target were calculated for all the cases.Results: The maximum point dose in the heart is 140, 125 and 115% of the reference point for Co-60, 6 and 10 MV, respectively. The INTEGRAL DOSE for the largest A-P patient was found to be 55.33, 54.17 and 51.66 Gy.Kg for Co-60, 6 and 10 MY, respectively. In using 10 MY beam, 7% reduction in the INTEGRAL DOSE of the heart was obtained. Alternatively, by using 6 MV beam, a reduction of only 2% was observed. The INTEGRAL DOSE of the heart for the 10MY beam had a 5% reduction in comparison to 6 MY beam.Discussion and Conclusion: Since lower energy beams cause a higher INTEGRAL DOSE to the heart and cord, the use of higher energy photon beams in the case of deep seated tumors and large size patients are unavoidable. In spite of the advantages of cobalt machines, its energy is not suitable for deeply suited tumors.

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APA: Copy

NEDAIE, H., GHARAATI, H., ZAHEDI, K., & KAZEMIAN, A.. (2005). CALCULATION AND COMPARISON OF HEART INTEGRAL DOSE IN THE TREATMENT OF ESOPHAGUS CANCER WITH THREE PHOTON ENERGIES & USING CT SIMULATION AND TREATMENT PLANNING SYSTEM. IRANIAN JOURNAL OF MEDICAL PHYSICS, 2(7), 77-84. SID. https://sid.ir/paper/96897/en

Vancouver: Copy

NEDAIE H., GHARAATI H., ZAHEDI K., KAZEMIAN A.. CALCULATION AND COMPARISON OF HEART INTEGRAL DOSE IN THE TREATMENT OF ESOPHAGUS CANCER WITH THREE PHOTON ENERGIES & USING CT SIMULATION AND TREATMENT PLANNING SYSTEM. IRANIAN JOURNAL OF MEDICAL PHYSICS[Internet]. 2005;2(7):77-84. Available from: https://sid.ir/paper/96897/en

IEEE: Copy

H. NEDAIE, H. GHARAATI, K. ZAHEDI, and A. KAZEMIAN, “CALCULATION AND COMPARISON OF HEART INTEGRAL DOSE IN THE TREATMENT OF ESOPHAGUS CANCER WITH THREE PHOTON ENERGIES & USING CT SIMULATION AND TREATMENT PLANNING SYSTEM,” IRANIAN JOURNAL OF MEDICAL PHYSICS, vol. 2, no. 7, pp. 77–84, 2005, [Online]. Available: https://sid.ir/paper/96897/en

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