EFFECTS OF PROPOFOL ON THE ARTERIAL BLOOD PRESSURE, BLOOD GASES AND VITAL SIGNS OF CAT

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NADAF H.; AVIZEH R.; RAAZI JALALI M.; RASEKH A.; MOHAMMAD KHANI Z.

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Journal: SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL Year:2007 | Volume:3 | Issue:1 (14) Page(s): 95-102

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Title

EFFECTS OF PROPOFOL ON THE ARTERIAL BLOOD PRESSURE, BLOOD GASES AND VITAL SIGNS OF CAT

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Keywords

ANESTHESIAQ2

PROPOFOLQ3

BLOOD GASESQ3

BLOOD PRESSUREQ3

CATQ3

Abstract

Every anesthetic agent has advantages and disadvantages including complication in cardiovascular, respiratory and thermoregulatory mechanisms. PROPOFOL was reported to be a short-acting agent, characterized by rapid recovery which can produce respiratory and cardiovascular depression. The effects of PROPOFOL administration on arterial BLOOD PRESSURE, heart rate, arterial blood pH, BLOOD GASES, temperature and respiratory rates were recorded in eight healthy stray CATs. All CATs were induced intravenously with 6 mg/kg of the PROPOFOL and were continued by infusion of the same drug (0.5mg/kg/min) for 60 minutes. All baseline measurements were obtained before induction (time 0) and 5, 10, 15, 30, 45 and 60 minutes after induction. An intravenous CATheter was inserted in femoral artery for collecting blood samples and arterial BLOOD PRESSURE measurements. Statistical analysis was performed by ANOVA method including repeated measure design and least significant difference. In this study temperature, heart and respiratory rates, pH, PaO2 and mean arterial BLOOD PRESSURE were significantly decreased during ANESTHESIA specially from 30 minutes after induction (P<0.05). Only partial pressure of carbon dioxide (PaCO2) values were increased significantly after induction of ANESTHESIA (P<0.05). It is concluded that infusion of PROPOFOL in CATs has limited application in surgery unless anesthetic depth is monitored. The major adverse effect of PROPOFOL was respiratory depression, and artificial ventilation of CATs during PROPOFOL administration is recommended.

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APA: Copy

NADAF, H., AVIZEH, R., RAAZI JALALI, M., RASEKH, A., & MOHAMMAD KHANI, Z.. (2007). EFFECTS OF PROPOFOL ON THE ARTERIAL BLOOD PRESSURE, BLOOD GASES AND VITAL SIGNS OF CAT. SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, 3(1 (14)), 95-102. SID. https://sid.ir/paper/97485/en

Vancouver: Copy

NADAF H., AVIZEH R., RAAZI JALALI M., RASEKH A., MOHAMMAD KHANI Z.. EFFECTS OF PROPOFOL ON THE ARTERIAL BLOOD PRESSURE, BLOOD GASES AND VITAL SIGNS OF CAT. SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL[Internet]. 2007;3(1 (14)):95-102. Available from: https://sid.ir/paper/97485/en

IEEE: Copy

H. NADAF, R. AVIZEH, M. RAAZI JALALI, A. RASEKH, and Z. MOHAMMAD KHANI, “EFFECTS OF PROPOFOL ON THE ARTERIAL BLOOD PRESSURE, BLOOD GASES AND VITAL SIGNS OF CAT,” SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, vol. 3, no. 1 (14), pp. 95–102, 2007, [Online]. Available: https://sid.ir/paper/97485/en

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