MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus

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MOHAMMADPOUR MEHRDAD; Masoumi Ahmad; DEHGHAN MAHMOUD; HASHEMIAN MOHAMMAD NASSER; Karami Shahab Addin; MAHMOUDI ALIREZA

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Journal: Journal of Ophthalmic and Vision Research Year:2020 | Volume:15 | Issue:4 Page(s): 486-492

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Title

MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus

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Keywords

Corneal Collagen Crosslinking

Keratoconus

MyoRing

Abstract

Purpose: To evaluate the safety and efficacy of femtosecond laser-assisted MyoRing implantation with concurrent Corneal Collagen Crosslinking (CXL) compared to MyoRing alone for the treatment of progressive Keratoconus. Methods: A total of 60 patients were enrolled in this randomized controlled trial. The patients were randomly allocated into two groups. In the first group, MyoRing was implanted, while in the second, it was inserted in the corneal stroma using the same technique, along with simultaneous CXL. Visual, refractive, topographic, and abberometric outcomes were measured preoperatively and at every postoperative visit. Results: Data of 47 patients were available at the end of the study; 28 in the MyoRing group and 19 in the MyoRing + CXL group. The mean uncorrected distance visual acuity (UDVA) improved from 0. 79 ± 0. 39 logMAR to 0. 52 ± 0. 31 logMAR (P < 0. 05) in the MyoRing + CXL group and from 0. 65 ± 0. 38 logMAR to 0. 62 ± 0. 23 logMAR (P = 0. 70) in the MyoRing group. CDVA changed from 0. 33 ± 0. 19 logMAR to 0. 25 ± 0. 16 logMAR (P = 0. 10) in the MyoRing + CXL group and 0. 32 ± 0. 22 logMAR to 0. 33 ± 0. 17 logMAR (P > 0. 50) in the MyoRing group. The mean keratometry (Km) decreased from 47. 5 ± 2. 7 D to 43. 8 ± 3. 2 D (P < 0. 001) in the MyoRing group and 49. 3 ± 3. 4 D to 45. 1 ± 3. 0 D (P < 0. 001) in the MyoRing + CXL group. Besides, horizontal coma was significantly lower in the MyoRing + CXL group (P = 0. 022). Conclusion: MyoRing insertion combined with CXL is a safe and effective method for the treatment of Keratoconus. The visual and topographic outcomes were comparable to that for MyoRing insertion after 10 months; however, horizontal coma was significantly lower in the MyoRing + CXL group.

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APA: Copy

MOHAMMADPOUR, MEHRDAD, Masoumi, Ahmad, DEHGHAN, MAHMOUD, HASHEMIAN, MOHAMMAD NASSER, Karami, Shahab Addin, & MAHMOUDI, ALIREZA. (2020). MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 15(4), 486-492. SID. https://sid.ir/paper/975284/en

Vancouver: Copy

MOHAMMADPOUR MEHRDAD, Masoumi Ahmad, DEHGHAN MAHMOUD, HASHEMIAN MOHAMMAD NASSER, Karami Shahab Addin, MAHMOUDI ALIREZA. MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus. JOURNAL OF OPHTHALMIC AND VISION RESEARCH[Internet]. 2020;15(4):486-492. Available from: https://sid.ir/paper/975284/en

IEEE: Copy

MEHRDAD MOHAMMADPOUR, Ahmad Masoumi, MAHMOUD DEHGHAN, MOHAMMAD NASSER HASHEMIAN, Shahab Addin Karami, and ALIREZA MAHMOUDI, “MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus,” JOURNAL OF OPHTHALMIC AND VISION RESEARCH, vol. 15, no. 4, pp. 486–492, 2020, [Online]. Available: https://sid.ir/paper/975284/en

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