ALBENDAZOLE INDUCES CELL DEATH IN HUMAN COLORECTAL CANCER CELL LINE HT-29

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HOVEIZI ELHAM; MOHAMMADI TAYEBEH

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Journal Paper

Paper Information

Journal: Medical Sciences Journal of Islamic Azad University,Tehran Medical Branch Year:2018 | Volume:28 | Issue:3 Page(s): 207-211

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Title

ALBENDAZOLE INDUCES CELL DEATH IN HUMAN COLORECTAL CANCER CELL LINE HT-29

Author(s)

HOVEIZI ELHAM | MOHAMMADI TAYEBEH | Issue Writer Certificate

Keywords

ALBENDAZOLQ3

MTTQ2

CANCERQ2

CELL DEATHQ2

Abstract

Background: It is a continuing effort to develop new anticancer drugs. It has been reported that ALBENDAZOLe has antiproliferative effects on several tumor cell lines. The aim of this study was to evaluate the killing effect of ALBENDAZOLe on HT-29 human colorectal CANCER cells. Materials and methods: Cultured HT-29 cells were treated with ALBENDAZOLe in 0. 1, 1 and 10 µ g/ml concentrations for 1, 3 and 5 days. Cellular viability and proliferation were evaluated by MTT and Trypan blue assays at determined days after treatment. Results: The comparison of cells count and viability in control group and treated groups with ALBENDAZOLe at different concentrations showed significant differences in days 1, 3 and 5. Conclusion: ALBENDAZOLe can suppress HT-29 cells proliferation and induces CELL DEATH in a dose and time dependent manner.

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APA: Copy

HOVEIZI, ELHAM, & MOHAMMADI, TAYEBEH. (2018). ALBENDAZOLE INDUCES CELL DEATH IN HUMAN COLORECTAL CANCER CELL LINE HT-29. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 28(3 ), 207-211. SID. https://sid.ir/paper/98694/en

Vancouver: Copy

HOVEIZI ELHAM, MOHAMMADI TAYEBEH. ALBENDAZOLE INDUCES CELL DEATH IN HUMAN COLORECTAL CANCER CELL LINE HT-29. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2018;28(3 ):207-211. Available from: https://sid.ir/paper/98694/en

IEEE: Copy

ELHAM HOVEIZI, and TAYEBEH MOHAMMADI, “ALBENDAZOLE INDUCES CELL DEATH IN HUMAN COLORECTAL CANCER CELL LINE HT-29,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 28, no. 3 , pp. 207–211, 2018, [Online]. Available: https://sid.ir/paper/98694/en

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