DOES ANTIBIOTIC REDUCE THE SEVERITY OF POST STREPTOCOCCAL GLOMERULONEPHRITIS?

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HOUMAN N.; OTUKESH H.; FARGAH F.

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Journal: Razi Journal of Medical Sciences Year:2007 | Volume:14 | Issue:56 Page(s): 219-224

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Information Journal Paper

Title

DOES ANTIBIOTIC REDUCE THE SEVERITY OF POST STREPTOCOCCAL GLOMERULONEPHRITIS?

Author(s)

HOUMAN N. | OTUKESH H. | FARGAH F. | Issue Writer Certificate

Keywords

GLOMERULONEPHRITISQ3

STREPTOCOCCUSQ4

ANTIBIOTICQ3

RENAL FAILUREQ3

Abstract

Abstract Background & Aim: ANTIBIOTIC treatment prevents new episode of Acute Post Streptococcal GLOMERULONEPHRITIS (APSGN). In this study we evaluated the correlation of ANTIBIOTIC therapy and the severity of APSGN in children. Patients and Methods: Between 1989 and 2001, files of all patients with diagnosis of GLOMERULONEPHRITIS were reviewed retrospectively. Inclusion criteria were: 1- hematuria, 2- evidence of recent streptococcal infection (Rising ASO titer or positive culture) and 3-transient decrease of C3. According to the history of ANTIBIOTIC usage for infection, the patients were divided in two groups. The severity of clinical and laboratory findings on admission were scored 0 to 4. T-student and Chi square were used for comparing means and frequency, respectively. P value less than 0.05 was considered significant. Results: Eighty six children with average age (SD) of 8.76(2.85) years were included in our study. The most frequent clinical presentations were as follows: hematuria (100%), edema and azotemia (70%), hypertension (68%), and proteinuria (53%). Meanwhile 53 cases had no history of ANTIBIOTIC usage. The severity of edema (defined by more than 3 plus) (37.3% vs 18.2%), duration of hospitalization (11 vs 8.9 days) and maximum serum creatinine (2 vs 1.3 mg/dl) were significantly higher in that group which did not receive ANTIBIOTICs.

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References

CORRELATION OF THE SEVERITY OF INITIAL CLINICAL AND LABORATORY FINDINGS WITH PROGNOSIS IN CHILDREN WITH POST STREPTOCOCCAL GLOMERULONEPHRITIS IN ALI ASGAR CHILDREN’S HOSPITAL

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APA: Copy

HOUMAN, N., OTUKESH, H., & FARGAH, F.. (2007). DOES ANTIBIOTIC REDUCE THE SEVERITY OF POST STREPTOCOCCAL GLOMERULONEPHRITIS?. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 14(56), 219-224. SID. https://sid.ir/paper/9930/en

Vancouver: Copy

HOUMAN N., OTUKESH H., FARGAH F.. DOES ANTIBIOTIC REDUCE THE SEVERITY OF POST STREPTOCOCCAL GLOMERULONEPHRITIS?. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2007;14(56):219-224. Available from: https://sid.ir/paper/9930/en

IEEE: Copy

N. HOUMAN, H. OTUKESH, and F. FARGAH, “DOES ANTIBIOTIC REDUCE THE SEVERITY OF POST STREPTOCOCCAL GLOMERULONEPHRITIS?,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 14, no. 56, pp. 219–224, 2007, [Online]. Available: https://sid.ir/paper/9930/en

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