It appears that one of the most significant outstanding effects of Eqbal’s thoughts has been the introduction of critical epistemology of western philosophy (as well as eastern philosophy in Persian philosophical process). In this trend of critic of philosophers and their epistemological methods in general, only those who are following his lead will be blessed with the light of his guidance. Hegel and Nietzsche, who have been briefly discussed during the course of this article, are the representatives of two western philosophical genres: one with an idealistic notion and the other with a moralistic manner. Eqbal recognizes numerous intellectual defects in both of them. Eqbal maintains that the depth of oriental thoughts and religious epistemology, especially the one which relates to Islam, consist of such dynamics components which could dismiss pessimismdismiss pessimism, degeneration and recursion and that would encourage optimism, while providing an inspiring explanation and an spiritual interpretation about the universe. “Nature”, “history” and “human” are the sources of cognition and interpretation of the universe, which have been extracted from the holly Quran by Iqbal, who has suggested the titles of “the great Palladian experience” or “the great experimental human cognition” for them. Eqbal Lahoori gave a fresh meaning and a new spirit to the criticism and explanation of religious cognition. The height and the extent of this critic and explanation are such outstanding and immortal that no thoughtful researcher and religious scholar, in no part of the world would find himself needless of it.