Rhabdomyolysis is a common condition with potentially devastating complications, and only few therapeutic options are available for the treatment of acute Rhabdomyolysis. In this case, a 56-year-old male who had been drinking alcohol, presented to the emergency department for evaluation of slurred speech, ataxic gait, mood instability, and cognitive disorder. On admission, his creatine kinase (CK) level was 2882 U/L. Despite aggressive fluid repletion, his CK level continued to increase, peaking at 11350 U/L. On administration and after the fluid transfusion with isotonic saline, his CK levels and clinical symptoms improved dramatically. We report this case as it is a rare condition of rhabdomyolysis due to alcohol, with the intent to highlight its clinical features and paraclinical finding.