Aim: The purpose of this study was to describe the occurrence of self report Bloating and related factors in patients with irritable bowel syndrome (IBS).Background: Bloating symptoms are common in patients with IBS and have significant impact on normal daily function. Patients and methods: This study was a community-based cross-sectional survey that conducted using a valid questionnaire base on Rome III criteria. Univariate analysis was used for investigation about distribution of self reported Bloating according to demographic and psychological factors in irritable bowel syndrome patients. Results: Out of 18180 subjects under study, 198 cases met criteria for the diagnosis of the irritable bowel syndrome according to criteria ROME III and 61.6% reported Bloating symptoms. Bloating symptoms were more prevalent among patients with intermittent symptoms and diarrhea than in patients with constipation. Catastrophic events and depression were independent risk factors for Bloating.Conclusion: Findings of this study support the clinical impression regarding the high prevalence of Bloating symptoms in patients with irritable bowel syndrome. Further studies are needed to understand the role of physiological and psychological factors and their interaction in development of Bloating in irritable bowel syndrome patients.

Background: Functional abdominal Bloating is one of the functional gastrointestinal disorders (FGIDs). Here, we aimed to investigate and compare the effects of probiotics and colloidal bismuth subcitrate on abdominal Bloating. Methods: This was a double-blinded randomized clinical trial performed on 125 patients with functional abdominal Bloating in Isfahan in 2020-2021. At the beginning of the study, information on the frequency of abdominal Bloating, its severity, the occurrence of early satiety, frequency of borborygmus, frequency of belching, and the frequency of defecation per week was collected. Patients were divided into 3 groups receiving familact probiotic pills that contained 7 bacterial strains, colloidal bismuth subcitrate tablets, and placebo pills for 4 weeks. Afterwards, the frequency and severity of abdominal Bloating and other symptoms were compared. Results: After 2 weeks, patients in the probiotic group had a significantly lower frequency of abdominal Bloating compared to other groups (P= 0. 006). After 4 and 8 weeks, patients in the probiotic group and bismuth group had a lower frequency of Bloating )3. 18±, 3. 02, 4. 11±, 3. 34) compared to placebo (5. 10±, 3. 54) (P= 0. 001 and P= 0. 037, respectively). During the study, patients in the probiotic group had a significantly lower Bloating severity (41. 90% had no symptom) compared to bismuth and placebo groups (12. 50, 12. 00% had no symptom) (p< 0. 05). The frequency of borborygmus was significantly lower in the probiotic group after 2 and 4 weeks during the study compared to other groups (1. 62±, 0. 2 Vs 2. 69±, 0. 3, 2. 45±, 0. 3 ) (P= 0. 010 and P= 0. 013, respectively). Conclusion: According to our data, consumption of probiotics improves the frequency and severity of abdominal Bloating and reduces borborygmus. Colloidal bismuth subcitrate also has significant effects.

Background: Functional abdominal Bloating (FAB) is a subjective sensation of increased abdominal pressure. Musculoskeletal factors may be related to functional abdominal Bloating, but this association has not been investigated. The present study compares trunk-related musculoskeletal factors (spinal alignment and abdominal muscle function) in females with and without FAB. Methods: This is a protocol study of a case-control study that will be conducted in females with (n=45) and without FAB (n=45), aged 18-60 years. A specially designed load cell setup and a flexicurve ruler will be used for the measurements of static abdominal muscle force and endurance, thoracic kyphosis, and lumbar lordosis, respectively. Additionally, skeletal muscle mass will be measured using body composition analysis. Depending on data distribution, an independent t-test or Mann-Whitney test will be used to determine differences in variables between the two groups. A multiple logistic regression will be used to investigate the adjusted associations of the trunk-related musculoskeletal variables and associations of the trunk-related musculoskeletal variables with functional abdominal Bloating.