Background and Aim: Plasma is commonly known as the fourth state of matter. Cold atmospheric pressure plasma (CAPP) is a new, simple, and non-invasive approach that has become popular in various fields. Due to its potential antibacterial properties, it has become a widely used disinfectant in clinical science. It has even been employed for therapeutic purposes, such as cancer treatment and wound healing. This review aims to introduce CAPP as a new approach for management of periodontitis and peri-implantitis.
Materials and Methods: A search was conducted in Scopus, PubMed and Web of Science databases for articles published between 2000 and 2023 using the keywords: “plasma gases”, “non-thermal atmospheric pressure plasma”, “cold atmospheric pressure plasma”, “cold plasma”, “periodontal”, “periodontitis” and “peri-implantitis”.
Results: The results showed that CAPP is effective for reducing the bacterial load and inflammation, modification of implant surfaces, promoting tissue regeneration, and improvement of clinical parameters. The use of CAPP in periodontal therapy and management of peri-implantitis is still in its early stages but studies have shown promising results.
Conclusion: CAPP appears to be a promising adjuvant therapy for periodontitis and management of peri-implantitis. However, further clinical studies are needed to fully explore its potential and determine its effectiveness for this purpose.