Acute hemorrhagic Edema of infancy is a distinctive, cutaneous small vessel leukocytoclastic vasculitis of young children with dramatic characteristic skin findings. It is characterized by lowgrade fever, erythematous Edema, and purpuric lesions mainly on the face and extremities. Visceral involvement is uncommon, and spontaneous recovery usually occurs within one to three weeks without sequelae. The main differential diagnosis is Henoch-Schonlein purpura. We report this case to highlight the condition and emphasize its benign nature. We describe a classic case of acute hemorrhagic Edema of infancy, and comment on the clinical features, pathology, treatment, and prognosis. The disease has spontaneous recovery without sequelae.

Diabetic macular Edema (DME) is arguably one of the most important challenges in ophthalmology. Macular Edema refractory to laser photocoagulation remains the most prevalent cause of untreatable vision loss in diabetes and is responsible for visual disability in millions of people worldwide. The lack of an effective therapeutic solution accounts for the range of interventions proposed. These include intraocular delivery of corticosteroids and anti- VEGF antibodies, and the surgical alternative of vitrectomy with or without removal of the internal limiting membrane (ILM).

The Present report describes a 5- years- old girl who presented with hypoproteinaemia and generalized oEdema due to giardiasis. She recovered fully 2 week after treatment with oral metronidazole. The emphasis is on the importance of giardiasis in children with hypoproteinaemia of obscure aetiology.

A 34 day-old girl infant was admitted for poor feeding and cholestasis. She had a bulging fontanelle, with no evidence of intracranial infection or hemorrhage. Investigations demonstrated that she had galactosemia. Computed tomographic scans demonstrated the presence of diffuse cerebral Edema. After treatment the Edema resolved.