Background: Gallstone disease is one of the most common digestive diseases in developed and developing countries. Recent studies have expressed evidence in the context of the role of nutrition in the Gallstone disease etiology. Thus, the main objective of present study was to investigate dietary patterns in patients with Gallstone among those admitted to Imam Reza hospital in Mashhad (Northeastern Iran). Methods: In this case-control study conducted in 2016 in Mashhad, demographic data from of 94 patients with Gallstones and 151 healthy controls matched for age, gender and socioeconomic variables was gathered via interviews and questionnaires. To determine the dietary patterns a valid and reliable 160-item semi-quantitative food frequency questionnaire was used. Nutritional software Nut 4 was used to analysis FFQ. Statistical tests and questionnaire analysis were performed by Nut 4 software (α,= 0. 05). Findings: Two major dietary patterns were identified: unhealthy (red meat, high-fat dairy, desserts, sugar, sweets, fast food, soft drink, snacks, sweet coffee, chowder, tea, fried potatoes, refined grains, egg, legume and potato), healthy (fish, fruits, vegetables, whole grains, poultry, nuts, dried fruits, dark coffee and low-fat dairy). Weight, waist circumference, and BMI had a direct relationship with Gallstone. Conclusion: This study showed that unhealthy dietary pattern, the consumption of TFA, SFA, legume and coffee, smoking and high body mass index increase the risk of Gallstone. Moreover, healthy dietary pattern, rich sources of vitamin C, fruits and vegetables do not contribute to Gallstone.

Background: Identification of the causes of Gallstone would result in better planning for the prevention of this disease. One of the proposed risk factors for this problem is Helicobacter pylori(H. pylori) infection. Objectives: The purpose of this study was to determine the incidence rate of Gallstone in patients with H. pylori gastritis. Methods: This was an observational study performed as a descriptive-comparative cross-sectional survey. We enrolled 169 consecutive patients with H. pylori gastritis admitted to Imam-Hossein Hospital, Tehran, Iran, in 2018, and Gallstone frequency in them was determined and compared with other variables. Results: Overall, 14 (8. 3%) patients had Gallstone, and all the patients had H. pylori gastritis. There was no significant association between Gallstone and H. pylori gastritis (P = 0. 561). Conclusions: It may be concluded that Gallstone frequency in patients with H. pylori gastritis is low, and there is no significant association between these two conditions.

Gastrointestinal obstruction by a Gallstone is an uncommon but important complication of biliary stone disease which mostly affects the elderly. The classic triad of radiological features includes pneumobilia, ectopic Gallstone and evidence of intestinal obstruction. Terminal ileum is the most common site of obstruction, followed by jejunum and gastric outlet. We present a case of duodenal Gallstone ileus of a large, fluid-density mixed biliary stone with a peripheral rim of hyperdensity (very fine calcification) in CT scan.

Backgrounds and Objectives: Bile stagnation leads to cholesterol concentrates and Crystal formation that are gall stone precursors. Cholecystokinin kinase hormone receptor (CCKAR) role in contraction and depletion of gall bladder. Polymorphisms of this receptor could have some role in gall bladder stone formation.Materials and Methods: Study on 116 Gallstone cases and 118 healthy controls were performed. For molecular analysis, amplification of polymorphism containing sequence was obtained by polymerase chain reaction and then genotyping were carried out by restriction fragment length polymorphism. Finally statistical analysis had carried out for detection of association.Results: With case-control study we recognize that C/T genotype in rs1800857 polymorphism increases gall stone risk more than 3 times (P=0.035; OR=2.954; CI95%=1.072-8.14).Conclusion: This analysis confirms previous studies on rs1800857 polymorphism susceptibility to gall stone only in female and clarify the importance of this region to make a disease prediction.