Background. One of the most popular complication of dental implants is periimplantitis which if not treated may lead to dental implant failure, there are different major causes of periimplantitis such as poor oral hygiene, lack of attached gingiva, poor Prosthesis, … … Here we are going to discuss the Prosthesis related periimplantitis, how to diagnose and how to manage and the preventive solutions Methods. The methods by which we can prevent the Prosthesis related periimplantitis and the signs and symptoms of disease is very important in long term survival of dental implants Results. The rate of Prosthesis related periimplantitis is high, and the supposed role of it in implant failures is obvious. Conclusions. As the most important factor in long term failure of implants, Prosthesis is of great importance, so the process and the guidelines should be carefully followed.