Objectives: Transconjunctival sutureless Vitrectomy (TSV) is a common procedure in eye surgery and is performed with needles 20, 23, and 25. This study compared the 2 methods of 20 and 23 in terms of various parameters. Materials and Methods: A total of 36 patients were admitted to Nikookari hospital, from which 18 patients were operated with the standard 20G Vitrectomy and 18 patients with 23G TSV. Intraocular pressure (IOP), corneal anterior surfacebased keratometry, corneal anterior surface-based curvature radius, and the corneal thinnest part thickness were evaluated before, a week after, and one month after the surgery. The results were compared through statistical methods using the SPSS software, version 22. Results: Based on the results, IOP, corneal anterior surface-based keratometry, corneal anterior surface-based curvature radius, and corneal thinnest part thickness had no significant difference between the 2 methods at different times (P > 0. 05). However, IOP significantly reduced in the 20G standard Vitrectomy one week after the surgery (P = 0. 023). However, K1 and K2 in the 20G standard Vitrectomy significantly increased one week after the surgery compared to the time before surgery (P < 0. 05). In addition, the corneal thinnest part thickness in the 23G TSV significantly increased a week after the surgery compared to the period before the surgery (P = 0. 007). Conclusions: In general, no statistically significant difference was observed between the 2 methods in terms of the studied parameters using one week and one month after the surgery.

Purpose: To evaluate the visual outcomes and surgical results of pars plana Vitrectomy for diabetic macular edema unresponsive to laser therapy using optical coherence tomography (OCT).Materials & Methods: Standard pars plana Vitrectomy with separation of posterior hyaloid was performed in 19 eyes of 17 patients with diabetic macular edema unresponsive to laser therapy (after 4 months). The macular thickness was evaluated before and after surgery with OCT. Slit lamp examination and visual acuity measurement were performed periodically.Results: After follow up of 3 months, visual acuity improved in 13 cases, decreased in 2 cases and was unchanged in four patients. The postoperative foveal thickness (374.7±114.9) was thinner than the preoperative foveal thickness (512.5±162) that was statistically significant (p=0.002). Postoperative complications included cataract formation (4 cases) and vitreous hemorrhage in one case. Conclusion: In eyes with persistent macular edema unresponsive to laser therapy, Vitrectomy appears to be beneficial in decreasing macular thickness and improving visual acuity.