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Author(s): 

Fardian Rahim Fardian" target="_blank">Rahim Fardian Rahim Fardian | Keyhan Javad | Fardian Rahim

Issue Info: 
  • Year: 

    2022
  • Volume: 

    1
  • Issue: 

    68
  • Pages: 

    179-201
Measures: 
  • Citations: 

    0
  • Views: 

    116
  • Downloads: 

    0
Abstract: 

The purpose of this research is to investigate the factors affecting the formation of leading schools, so that it can be used in Iran's education. For this purpose, first, according to the research background and theoretical foundations, a conceptual framework was presented in the field of the components of an efficient and progressive school. Due to the nature of the subject, this research is an applied and developmental research and its method is of a mixed type, and includes quantitative and qualitative methods. According to the obtained information, the statistical population is about 3000 people. The sample size is estimated to be 344 people using Morgan's table. Stratified sampling method was used for sampling in this research, and 84 managers and 260 teachers participated in this study. The tool of this research is a researcher-made questionnaire. To analyze the data and answer the research questions, the correlation coefficient test and factor analysis were used. The results of the research showed that the components of management and leadership, research factors, educational factors, human resources, budget and infrastructure, technology and equipment are the main components of the formation of leading schools, and the component of educational factors has the largest contribution.

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Issue Info: 
  • Year: 

    2017
  • Volume: 

    25
  • Issue: 

    131
  • Pages: 

    11-16
Measures: 
  • Citations: 

    0
  • Views: 

    1231
  • Downloads: 

    0
Abstract: 

Background and Objective: Bordetella pertussis is a gram-negative cocobacilli bacterium and etiologic agent of whooping cough that in recent years, the number of its cases is on the rise. The ability of biofilm production helps this bacterium in interference with host immune system, severity of illness and antibiotic sensitivity. Thus, due to the importance of this factor, in this investigation, we tested the ability of Bordetella pertussis isolates in biofilm formation.Materials and Methods: Nasopharyngeal samples were collected from persons who suspected whooping cough from throughout of Iran from 2014 to 2016 and were transferred to pertussis reference laboratory in Pasteur Institute of Iran. The bacterium in question was isolated by culture so that finally we had 20 positive samples. At the end, we performed in vitro biofilm formation test for isolated strains.Results: All of the 20 clinical samples of Bordetella pertussis which in this study were examined could form biofilm and their final OD became between 0.606 and 1.212, the power of the biofilm made by them was intermediate. Conclusion: Findings of this study was similar to researches conducted by other researchers, which showed the ability of the strains of Bordetella pertussis to form biofilm and to create adverse effects on the host for example antibiotic resistance, illness severity, and so on. Thus, considering the importance of this issue, more and broader researches are needed in this area.

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Issue Info: 
  • Year: 

    1390
  • Volume: 

    0
Measures: 
  • Views: 

    673
  • Downloads: 

    0
Abstract: 

مقدمه: عصاره کندر از قدیمی ترین داروهای تجویزی در طب باستانی هند و چین و نیز طب سنتی ایرانی برای درمان بیماری نورودژنره آلزایمر بوده است و نیز از اصلی ترین بخشهای عصاره کندر، بتابوسولیک اسید (BBA) می باشد. دکتر ریاضی و همکاران اخیرا در گزارشی نشان داده اند که اثر BBA بر روی سلولهای بنیادی عصبی، باعث پایداری میکروتوبولها می گردد. ما در این مطالعه، اثر BBA را بر روی سلولهای بنیادی جنینی مورد بررسی مولکولی در سطح mRNA قرار داده ایم. سلولهای بنیادی، سلولهای پرتوانی هستند که توانایی تمایز بالقوه به رده های مختلف سلولی را دارند. یکی از پروتکل های تمایزی این سلولها، روش ساخت اجسام شبه جنینی (EB) است. در پروتکلهایی که هدف آن، تولید سلولهای عصبی می باشد، از مولکول شیمیایی رتینوئیک اسید استفاده می گردد که در اینجا تاثیر عصاره کندر و رتینوئیک اسید را در افزایش بیان ژنهای اختصاصی عصبی مورد سنجش قرار گرفته شده است.روش ها: در این مطالعه اثر عصاره کندر (حاوی ماده موثره (BBA و نیز مولکول رتینوئیک اسید (RA) و اثر ترکیبی این دو ماده را بر تغییرات میکروسکوپی و تغییرات نسبی بیان ژنهای اختصاصی، در تمایز سلولهای بنیادی جنینی بررسی شده است. سلول های بنیادی جنینی موشی (CGR8) کشت داده شده در محیط کشت KO-DMEM حاوی SR%10 و FBS%5، آنتی بیوتیک،LIF  با استفاده از تریپسین به شکل تک سلول درآمده، به نسبت2x104 cell/cm2 در پلیت با چسبندگی کم، کشت شدند. از روز دوم، پس از تشکیل اجسام شبه جنینی، در تیمارهای رتینوئیک اسید و BBA به ترتیب از غلظتهای 10-8 مولار و 10-5 مولار بکاربرده شد. روز ششم، از نمونه ها با استفاده از Trizol استخراج RNA صورت گرفت و با استفاده از تکنیک کمی Real-time PCR بیان نسبی ژنهای Nestin,OTX2 ,MAP2 مورد سنجش قرار گرفتند.یافته ها: در مشاهدات میکروسکوپی با میکروسکوپ نوری، در تیمارهای رتینوئیک اسید و رتینوئیک اسید همراه با BBA اجسام آپوپتوزی مشاهده شد. در ژنهای Nestin,OTX2 ,MAP2 نیز به ترتیب بیشترین بیان نسبی را در تیمار BBA همراه RA و بعد در تیمار RA و سپس در تیمار با BBA مشاهده گردید.بحث و نتیجه گیری: بتا-بوسولیک اسید (BBA) به عنوان ماده موثره کندر دارای ویژگی های درمانی در بیماران آلزایمری بوده است. این نقش را می توان در اثرات BBA در تمایز عصبی و پایداری میکروتوبولی آن جستجو کرد. با توجه به افزایش بیان ژن MAP2 در نمونه های تیمار شده با BBA و مطالعات صورت پذیرفته توسط دکتر ریاضی که ارتباط BBA و پروتئین وابسته به میکروتوبولها (MAP) را نشان می دهد، می توان این دیدگاه را پیشنهاد داد که BBA از طریق مسیرهای سیگنالینگ ناشناخته با واسطه MAP2 در زمان تمایز سلولهای بنیادی، می تواند مسیر تمایز را به سوی سلولهای عصبی هدایت کند. این مطالعه می تواند راه را برای بررسی غلظت های بهینه و فهم مسیرهای سیگنالینگ دخیل در این فرآیند را هموارتر سازد.

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Issue Info: 
  • Year: 

    2023
  • Volume: 

    13
  • Issue: 

    3
  • Pages: 

    123-141
Measures: 
  • Citations: 

    0
  • Views: 

    198
  • Downloads: 

    21
Abstract: 

A B S T R A C TThe morphology of each region is related to its landforms, the morphology of flat areas is related to inselbergs. The presence of inselbergs in desert and dry areas gives a special appearance to the morphology of these areas. The study of these landforms and the effective factors in their formation is considered a necessity in terms of regional development. According to the studies, various factors play a role in the formation of inselbergs, and the role of lithology seems to be more prominent. In this research, which was conducted with the method of field and library studies, we identified 18 inselbergs in Safi Abad plain and by studying them, we came to the conclusion that the inselbergs of this plain are mainly formed in sedimentary rocks such as limestone, conglomerate and sandstone. Among the geological formations, the largest and most diverse inselbergs in the Safiabad plain are formed in the mass conglomerate formation with good hardening because this formation is the most widespread in this plain. But the most typical inselbergs of this plain are formed in thick layered limestone. Because this formation is more resistant to erosion. Lar Formations including Limestone and Thick Limestone’s to Mass Dolomite and Delichai Formations have also played an important role in the formation of inselbergs in this plain. Although the extent of these formations is not significant, but due to their significant resistance to erosion and being far from these processes, they have caused the formation of evolved inselbergs in this plainExtended AbstractIntroductionInselbergs are ridges with a height of less than 500 meters formed with a steep slope in the plains. Their resistance to erosion has caused them to be considered capable players in the morphology of arid and semi-arid regions. Due to their uniqueness in desert areas, these areas are of interest to tourists, and the economic situation of these areas can be improved by attracting tourists. The prominence of inselbergs in desert areas has caused researchers to pay attention to their studies, the most important of which are the studies of Pye in Kenya (1984), Nenonen in Finland (2018), Luiza in Brazil (2021), Laetitia in Africa (2019), and Mashaal in Egypt (2020). Although the conditions for inselberg formation are available in some areas of Iran, and these landforms have given a particular face to the morphology of this country, no significant study has been done on them so far. This research attempts to investigate the role of lithology in inselberg formation in Safi Abad Plain by using library and field studies. MethodologySafi Abad plain in the northeast of Iran and North Khorasan province and in terms of geographical coordinates between 36-˚ 48-05 to 36-22-55˚ North and 37-57˚ East to 36-˚ 37-08 It is located at 57-58-11 east. Field and library studies were used to study the inselbergs of this plain. The entire region was surveyed in 2 years in the field studies, and 18 inselbergs were identified. Then, the location and extent of their expansion were determined. In the morphometry that was done as a survey, the minimum height, length-to-width ratio of inselbergs, and their distance from each other were measured with GPS. The study of the concepts, definitions, and effective processes in inselberg formation was done with the library method. The maps of this research were drawn with Adobe Illustrator software. Results and discussionInselbergs are diverse in terms of morphology; in the studied area, 18 inselbergs were identified, most of which are mixed. Most of them are rocky and have less vegetation. Regarding lithology, inselbergs are particular forms of igneous and metamorphic rocks, but some are also formed in other rocks. Although lithology plays an essential role in inselberg morphology, it cannot be claimed that inselbergs formed in the same formation have the same shape. Although the dominant lithology of the Safi Abad plain is formed from sedimentary rocks, due to the different resistance of its formations, the height, shape, and slope of the inselbergs of this plain are different in different parts of the region. The difference in these characteristics has caused the different shapes of the land in this plain. According to the studies of the most resistant formations of Safi Abad plain against erosion, limestone is a thick layer of chert mass formed due to the resistance against the erosion of the complete inselbergs.After this formation, the Lar formation consists of fine-grained uniform dolomitic limestone with thick to massive layering, which is more resistant; that is why many inselbergs in the region have formed in it. The third formation in terms of resistance is the Apsin-Albin unit, which includes orbitolinate limestone and thick limes to a mass of dolomite. Although this unit has a small area, its inselbergs are closer to typical inselbergs. In terms of area, most of the area is composed of mass conglomerates with good hardening. Due to the different effects of this formation from different processes, its inselbergs do not have the same morphology. The inselbergs formed in this formation are in the middle part of the high area, low in the southern part, incomplete in the western part, and incomplete mushrooms in the path of the Gerati River. After this formation, gray shales are the most resistant to erosion. This formation, which belongs to the Jurassic period, has formed a large part of the northeastern inselbergs. The alternation of limestone and marl in the Delichai formations in the middle part of the region provides the basis for the formation of mushroom-shaped inselbergs in the future. ConclusionSafiabad Plain is in the northeast of Iran, and in terms of geomorphological units, it is part of central Iran. Inselbergs form part of the morphology of this plain. In this study, 18 inselbergs were identified in this plain, and their detailed study showed that their primary skeleton was established by tectonic activities in the Devonian to Miocene period with the formation of Posht Bahram mountains. It was formed when the tectonic activities calmed down and in opposition to the lithology and erosion of the inselbergs of this plain. In terms of lithology, the well-hardened conglomerate formation covers nearly 47% of this plain, and due to its large size and different distances from erosion processes, various inselbergs have been formed in it. The southern inselbergs formed in this formation have a regular shape due to wind and blue erosion. In contrast, the middle inselbergs have an incomplete shape due to the distance from higher erosion, and the western inselbergs have an incomplete shape due to the superiority of blue erosion. Another formation that plays a vital role in this field is Lar Mei Formation. Although this is the second formation in terms of size and strength, many inselbergs have formed in it. The Shemshak formation is placed after the Lar formation in terms of resistance. This formation has caused the formation of chain inselbergs in the northeast of the region. The most typical inselbergs of the region are observed in the thick layered limestones of the formation (Maastrichtian). Also, this research found that inselbergs may be formed in all flat areas of the world and even in sedimentary formations. However, the inselbergs formed are far from those formed in tropical regions' igneous and metamorphic formations. FundingThere is no funding support. Authors’ ContributionThe authors contributed equally to the conceptualization and writing of the article. All of the authors approthe contenttent of the manuscript and agreed on all aspects of the work declaration of competing interest none. Conflict of InterestThe authors declared no conflict of interest. Acknowledgments We are grateful to all the scientific consultants of this paper.

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Issue Info: 
  • Year: 

    2005
  • Volume: 

    18
  • Issue: 

    3 (44)
  • Pages: 

    31-37
Measures: 
  • Citations: 

    0
  • Views: 

    665
  • Downloads: 

    0
Abstract: 

Background and Aim: Preserving canal curvature during different phases of canal preparation is an important point. In Endodontic therapy all efforts are made to prepare canal in a way that final canal follows the primary canal curvature. The purpose of this study was to evaluate the efficacy of root canal preparation performed by students at Endodontic Department of Dental School, Tehran University of Medical Sciences. Materials and Methods: In this retrospective study, classic method of step- back technique was investigated for preserving canal curvature in mesial roots of first mandibular molars and mesiobuccal roots of first maxillary molars between years 2000 and 2004. A randomly selected sample of 400 dental patient records was investigated by 4 observers (Endodontic department professors), searching for procedural errors. A clear explanation sheet of curvature preservation and procedural errors such as ledge formation, apical foramen transportation, zipping and stripping and a questionnaire were prepared for observers. The observers went through reliability test and kappa value for agreement between every two observers. The results were above 0.8. Data were analyzed by EPI6 statistical computer program, using Chi-Square and Fisher exact test with P<0.05 as the limit of significance. Results: This study consisted of 152 first maxillary molars and 248 first mandibular molars. The prevalence of curvature preservation in mesial root of first mandibular molars and mesiobuccal root of first maxillary molars were 38.5% and 47.6% respectively. Procedural errors detected consisted of 33% ledge formation, 26.1% apical foramen transportation, 1.8% zipping and 4.1% stripping for mesial root of the first mandibular molars. The results for the first maxillary molars were 27%, 19%, 3.2% and 3.2% respectively. Conclusion: The study results revealed the efficacy of endodontic education and the proficiency of junior and senior students in preparing curved posterior root canals. The results obtained in this retrospective study are comparable to prospective studies.

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Journal: 

QURANIC DOCTRINES

Issue Info: 
  • Year: 

    2023
  • Volume: 

    20
  • Issue: 

    37
  • Pages: 

    181-211
Measures: 
  • Citations: 

    0
  • Views: 

    158
  • Downloads: 

    13
Abstract: 

Resistance is one of the fundamental Quranic values in the cause of the development of the Islamic society and the formation of the Islamic civilization, which means standing and resisting against something has upset the balance in internal and external dimensions. The formation of this value in the society as one of the methods of the conventional model of human life in the fields of human life; So that its manifestation can be observed in the totality of social behaviors, it is called the culture of resistance (Problem statement). The purpose of this article is the achievement of the engineering process of this value in a society based on the growth-oriented thought (ideological) system of the Holy Quran (Purpose). Now the question is what process does the Holy Quran propose in order to engineer the culture of resistance in the society? (Question). The necessity of examining this issue is clear considering the emphasis of religious teachings on this value and the need for Islamic societies, especially considering the current conditions of Islam and the need for convergence and coordination between the resistance front (Necessity). The research method in stating the engineering process and its components is qualitative content analysis with an analogy approach (Method). The findings of the research show that the engineering process of resistance culture is based on a self-awareness and purposefulness, according to the idea of Quranic growth, in a three-stage process that leads to the happiness of man and human society (Conclusion).

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Issue Info: 
  • Year: 

    2023
  • Volume: 

    17
  • Issue: 

    3
  • Pages: 

    354-360
Measures: 
  • Citations: 

    0
  • Views: 

    119
  • Downloads: 

    11
Abstract: 

2Background and Aim:  Staphylococcus haemolyticus is a prominent pathogen in hospital-related infections, exhibiting high antibiotic resistance. This study aimed to investigate antibiotic sensitivity, biofilm formation, and the presence of virulence-associated genes in S. haemolyticus isolated from pregnant women with urinary tract infections. Materials and Methods:  Clinical samples were collected from pregnant women with urinary tract infections between October 2021 and December 2022. S. haemolyticus isolates were identified using cultural, biochemical, and molecular methods. Antibiotic susceptibility was determined using the VITEK-2 system. Biofilm formation was assessed, and virulence-associated genes (hla, hlb, fnbA, and fnbB) were detected using PCR. Results: Among 260 clinical samples, 36 S. haemolyticus isolates were identified. The isolates exhibited high resistance to Benzylpencillin, Erythromycin, oxacillin, Trimethoprim/sulfamethoxazole, Levofloxacin, and Gentamicin. Resistance was lower to Tigecycline, linezolid, tobramycin, Rifampin, vancomycin, Moxifloxacin, Tetracycline, and Ticoplanin. Biofilm formation was negative in 69. 4% and weak in 30. 6% of isolates. The hla gene was present in all isolates, while hlb was detected in 77. 7%. Detection rates of fnbA and fnbB were 88. 8% and 38. 8%, respectively. Conclusion:  This study highlights the high antibiotic resistance, limited biofilm formation ability, and prevalence of virulence-associated genes in S. haemolyticus isolates from pregnant women with urinary tract infections. These findings underscore the clinical significance of this bacterium and the need for infection control measures

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Journal: 

BIOCHEMICAL JOURNAL

Issue Info: 
  • Year: 

    1996
  • Volume: 

    316
  • Issue: 

    PT 1
  • Pages: 

    1-11
Measures: 
  • Citations: 

    1
  • Views: 

    130
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

MILLER D.G.

Issue Info: 
  • Year: 

    1993
  • Volume: 

    -
  • Issue: 

    95
  • Pages: 

    0-0
Measures: 
  • Citations: 

    1
  • Views: 

    192
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

TABATABAEI A.

Issue Info: 
  • Year: 

    2011
  • Volume: 

    2
  • Issue: 

    2 (3)
  • Pages: 

    87-99
Measures: 
  • Citations: 

    1
  • Views: 

    2774
  • Downloads: 

    0
Abstract: 

The interaction between syntax and word-formation has been of great theoretical significance in the past four decades. The question that is now raised is as follows: is word-formation an independent module, or should it be subsumed under syntax?Considering word-formation processes in Persian, this article is an attempt to provide a number of facts in favour of the existence of an independent word-formation component. These facts are:1. A great number of complex words in Persian are headless, contrary to the syntactic phrases.2. A great number of the Persian compounds have meanings which are predictable, yet different from their compositional meanings.3. The syntactic category of a large number of the Persian compounds is different from that of their constituent words.4. The derivational suffix “-i”, while added to nouns, may make adjectives or nouns, according to which we need to devide the Persian nouns into two subgroups. But this distinction is irrelevant in syntax.5. The Persian inflectional morphemes do not occur inside compounds.6. Compounds and syntactic phrases have different stress patterns.

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