The honeybee, Apis mellifera L. (Hymenoptera: Apidae), is one of the most economically important insects because of long providing humans with honey and beeswax. In addition to honey production, honeybees are the principal species used for crop pollination worldwide (Free 1993). The pollination services of honeybees in the United States have been estimated to worth $14.6 billion in 2000 (Morse and Caldrone 2000). The honeybees have been recently used as vectors of beneficial pathogens to control those plant pathogenic pests that are associated with plant flowers (Shafir et al. 2006). Honey production and pollination of honeybees are negatively influenced by a variety of pests and diseases (Romeh 2009). The Varroa mite, Varroa destructor Anderson & Trueman (Acari: Varroidae), is probably the most important parasite of A. mellifera, causing tremendous damage to honey bees and great economic loss to the beekeeping industry. Parasitism by V. destructor may results in the loss of adult weight, severe wing deformations and reduced longevity of worker and drone honey bees (De Jong et al. 1982). Sever infestation can lead to reduced worker bee populations and collapse of untreated colonies, not only due to mite infestation, but also as a result of secondary viral, bacterial and fungal infestations (Hung et al. 1996).