Introduction: Social life skills include a group of skills necessary for coping with the situations and challenges of everyday life and equipping individuals in terms of knowledge, attitude, and behavior against returning to addiction. Therefore, the purpose of this study was to determine the role of social life skills in the Durable treatment of addiction in Kashan. Materials and Methods: This study used a combined method, and the statistical population included the three groups of therapists and researchers in the field of addiction, people succeeded in beating drug addiction and their families, as well as drug addiction patients in Kashan in 2018. A stratified purposeful sampling method was used, where 31 individuals were selected in a qualitative section, and 343 individuals in the quantitative section as the sample. The data collection technique was a semi-focused interview; in addition, the standard questionnaire of life skills and the data were analyzed using variance analysis (F) and the Pearson’ s correlation coefficient. Results: The lack of functional life skills in pre-drug addiction period created a context for addiction, and when it came to the drug use, it created an area for continued drug addiction. After starting to leave the drug, learning these skills led to a lasting improvement in the treatment and empowerment of the improved people. In addition, those in the state of constant withdrawal had more life skills (p=0. 001), and increasing the life skills of the individuals improved their sustainability (p= 0. 001). Conclusions: If individuals have skills, such as decision-making skills, not speaking, expressing, communicating, etc., or taking part in a skill-building program during a course of treatment, they will be more successful in leaving addiction.