The structure and organizational of Astan Quds at during the Qajar period, especially during the reign of Nasir al-Din Shah, was similar to that of the Safavid period and also, according to the instructions of Ali Shah petition in Afsharian period. This research seeks to investigate the distribution of Astan Quds offices and jobs in each of the sixth city neighborhoods of Mashhad, relying on the manuscript of the 'Ketabche Teadad Nefuse Arze Aqdas Va Shahre Mashhad Moqadas'. The manuscript was written in the kingdom of Nasir al-Din Shah and ordered by Mohammad Taqi Mirza Rokn al-Dawlah, the ruler of Khorasan and Sistan. This version is an interesting example of the information and statistics of the population and businesses of Mashhad during Nasir al-Din Shah, and shows the distribution of offices and jobs in Astan Quds in different neighborhoods of Mashhad. The research method in this study is an analysis of available data, which was analyzed using SPSS software. The results indicate a significant relationship between the dispersion of Astan Quds offices and jobs in the sixth district of Mashhad. This research shows that the number of high-ranking positions in the pyramid of the Astan Quds Organization is larger than the population in the Bala Khiaban and Sarab as a result of paganization and is much lower in the Paein Khiaban of the street, which was poorer.