Introduction: Trauma is one of the major issues threatening public health. Trauma is a leading cause of disability and mortality in all countries. This study aimed to explore and understand the challenges of early rehabilitation care in multiple trauma patients from the experience of a Multidisciplinary care team using a qualitative research method. Methods: This study was conducted with a qualitative research Approach using qualitative content analysis. Participants were seven nurses, two doctors, three physiotherapists, and two occupational therapists in inpatient and outpatient traumas were interviewed. Data were collected through semi-structured interviews with a purposive sampling continued until data saturation. Analysis of data collected concurrently for comparison was done. Results: First, for depth descriptions of the participant statements, 800 codes were extracted and finally, for the analysis, and constant comparison, two main themes of the lack of holistic care and support structure were extracted. Conclusion: The results showed that comprehensive and rehabilitation-based care was essential to achieve important goals in this group of patients. Understanding the challenges of early rehabilitation care in multiple trauma patients will help from health policymakers to solve these problems and help improve the health in multiple trauma patients.