In the rapidly evolving airline industry, the strategic importance of Maintenance, Repair, and Operations (MRO) has never been more critical. This study delves into the transformative role of Key Performance Indicators (KPIs) in enhancing the efficiency, effectiveness, and strategic alignment of MRO operations within the airline sector. Through a mixedmethods research design, incorporating both quantitative data analysis and qualitative insights from industry experts, the investigation offers a comprehensive understanding of how specific KPIs influence MRO operational performance and strategic decision-making. Findings reveal that operational efficiency KPIs, such as aircraft availability rate, mean time between maintenance, and parts availability rate, significantly impact MRO performance, contributing to improved operational reliability and financial health. The study also underscores the interplay between safety, quality, and customer satisfaction metrics, highlighting their collective importance in fostering airline reputation and success. Strategic implications suggest that airlines can achieve operational excellence and align MRO operations with broader business objectives through an integrated KPI framework, advanced technology utilization, and a culture of continuous improvement. This research not only bridges the gap between theory and practice in MRO management but also sets forth directions for future inquiry, particularly in the domains of emerging technologies and sustainability practices within MRO operations. The insights garnered from this study serve as a vital resource for airline executives, MRO practitioners, and academic researchers, guiding strategic enhancements in MRO operations to meet the challenges of the contemporary aviation landscape.