Considering that agricultural sector is the largest consumer of water, presenting integrated management for water resources and formulating effective policies to increase water productivity in this sector is essential. Therefore, using economic modeling, this study simulated the farmers’ responses to irrigation water pricing and rationing policies in Zabol city. To achieve the study purpose, the State Wide Agricultural Production Model and Positive Mathematical Programming were applied. The required data for the years 2010-2011 was collected by completing questionnaires and collecting data sets from the relevant agencies of Zabol city in personal attendance. The results showed that imposing irrigation water pricing and rationing policies in Zabol city leads to a reduction in the total cultivated area by 9.54 and 5.14 percent and a reduction in the water consumption by 6.23 and 7.01 percent, compared to the base year. Ultimately, irrigation water rationing policy, considering frugality of 18.9 million m3 of water, as the appropriate solution for the sustainability of water resources of Zabol city was proposed.