The subject of religious science has flourished in recent years in scientific circles, and the discussion of the new Islamic civilization has highlighted the possibility of Islamization of sciences in a special place. In this regard, and especially with the Corona epidemic, the issue of Islamic medicine was raised and provoked controversy between proponents and opponents. The question is what is the meaning of Islamic medicine and can a science called Islamic medicine be realized? On the basis of numerous medical narrations, the proponents emphasize the realization of Islamic medicine, and the opponents deny the possibility of the realization of Islamic medicine by justifying or distorting the narrations in the field of medicine and limiting the realm of religion, or by emphasizing the empirical dimension of this science. In this article, while explaining the different views on this topic with the libraryanalytical method, an attempt is made to provide a systemic-civilizational definition of religion, and then evidence will be provided on the influence of principles and presuppositions in modern medicine to judge the possibility of realizing the science of medicine with a religious and divine nature.