Background and aims: Nowadays, the Covid-19 has increasingly affected the health and economy of different societies. Therefore, it is important to identify approaches to deal with this disease by scientific methods and to support these approaches by people and governors. Thus, the present study tries to identify and prioritize the approaches to deal with the Covid-19 outbreak by statistical methods and novel operation research. Methods: The present study is a descriptive survey. In the first step, 46 approaches of dealing with the Covid-19 outbreak were classified into two groups of individual and government factors by reviewing and analyzing the previous studies. Then, with the help of experts and specialists, the proposed components were validated and qualified. In the final step, the selected approaches were prioritized and analyzed with the help of Best-Worst Method. Results: The final results is emphasized on the high impact of some individual factors such as “, timely vaccination, to observe the social distancing, and timely attendance at medical centers”,as well as some govermental factors such as “, speed in providing and implementing the national vaccination program, extensive screening, inexpensive and easy corona testing, and providing medicine, equipment and manpower for medical centers”,for dealing with the Covid-19 outbreak. Conclusion: Observance of individual considerations and correct policies of governmental factors, with the priorities mentioned in this study, can have a great impact on dealing dealing with the Covid-19 outbreak.